Question 1

How quickly does EpiPen start working?

Accepted Answer

Within 1–2 minutes you should notice breathing improvement and reduced swelling. Full effect occurs around 5–10 minutes.

Question 2

How long does the effect of one EpiPen last?

Accepted Answer

The clinical effect lasts about 20–30 minutes. That’s why you must go to hospital immediately – the reaction can return.

Question 3

When should I use a second EpiPen?

Accepted Answer

If symptoms have not improved or are getting worse 5 minutes after the first injection, use the second EpiPen.

Question 4

Does EpiPen work faster if injected into a vein?

Accepted Answer

Never inject into a vein – it can cause dangerous arrhythmias. Intramuscular injection into the thigh is optimal and safe.

Question 5

How long does adrenaline stay in your system after EpiPen?

Accepted Answer

Adrenaline itself is cleared within minutes, but its metabolites can be detected in urine for up to 24 hours.