Question 1

Can Sandrena cause weight gain?

Accepted Answer

Mild fluid retention may cause temporary weight gain of 1–2 kg during the first few months. This usually settles. Transdermal oestrogen is not associated with significant long‑term weight gain.

Question 2

Does Sandrena increase the risk of breast cancer?

Accepted Answer

Long‑term HRT (5+ years) is associated with a small increase in breast cancer risk, mainly with combined oestrogen‑progestogen therapy. Transdermal oestrogen alone may carry a lower risk, but regular breast screening remains essential.

Question 3

What should I do if I develop a skin rash after applying Sandrena?

Accepted Answer

Mild redness usually resolves within a few days. Rotate application sites and avoid tight clothing. If the rash is severe, itchy, or blistering, stop the gel and consult your doctor—it may indicate an allergic reaction.

Question 4

Can I drink alcohol while using Sandrena?

Accepted Answer

Moderate alcohol is generally safe. However, excessive alcohol may affect liver function and could theoretically alter oestrogen metabolism. It may also worsen hot flushes in some women.

Question 5

How soon after stopping Sandrena will side effects go away?

Accepted Answer

Mild side effects like breast tenderness usually resolve within 1–2 weeks of stopping. Serious risks (e.g., clot risk) return to baseline after a few months. Withdrawal symptoms (hot flushes) may return as hormone levels fall.