Question 1

How does Mounjaro suppress appetite?

Accepted Answer

Mounjaro activates GLP‑1 receptors in the hypothalamus, the brain’s appetite centre, making you feel fuller and reducing hunger signals. GIP may also contribute to this effect.

Question 2

How long does Mounjaro stay in your system?

Accepted Answer

The half‑life is about 5 days, so it takes roughly 30 days (5 half‑lives) for the drug to be completely cleared after your last injection.

Question 3

Can Mounjaro cause low blood sugar (hypoglycaemia)?

Accepted Answer

On its own, the risk is low because it stimulates insulin only when glucose is high. However, if combined with sulfonylureas or insulin, hypoglycaemia can occur – your doctor may adjust those medications.

Question 4

Why is Mounjaro injected only once a week?

Accepted Answer

The C20 fatty acid chain binds strongly to albumin, which acts as a circulating reservoir, slowly releasing tirzepatide over several days.

Question 5

How does Mounjaro compare to Wegovy or Saxenda?

Accepted Answer

Mounjaro targets both GIP and GLP‑1, while Wegovy and Saxenda target only GLP‑1. Clinical trials show Mounjaro leads to greater average weight loss.