Question 1

What is the most common side effect of Mysimba?

Accepted Answer

Nausea is the most frequent side effect, affecting more than 1 in 10 people. It usually improves within a few weeks, especially if you take the tablets with food.

Question 2

Can Mysimba cause weight gain instead of loss?

Accepted Answer

No, Mysimba is designed to promote weight loss. However, some people may experience fluid retention or increased appetite as a side effect, but this is uncommon.

Question 3

Should I stop Mysimba if I feel depressed?

Accepted Answer

If you experience new or worsening depression, or thoughts of self‑harm, stop the medicine and contact your doctor immediately. Do not restart without medical advice.

Question 4

Can I take painkillers like codeine with Mysimba?

Accepted Answer

No. Mysimba contains naltrexone which blocks opioids, so codeine, morphine, and similar painkillers will not work. Avoid all opioids.

Question 5

Does Mysimba affect blood pressure?

Accepted Answer

Yes, bupropion can increase blood pressure. Your doctor will check your BP before starting and regularly during treatment. If it rises significantly, treatment may need to be stopped.