Wegovy Pill (Semaglutide Tablets)
The Wegovy Pill (semaglutide tablets) is the first GLP‑1 receptor agonist weight‑loss treatment available in a once‑daily tablet form in the UK. It contains the same active ingredient as the Wegovy injection but is taken orally, offering a needle‑free alternative for adults living with obesity (BMI ≥30 kg/m²) or overweight (BMI 27 to <30 kg/m²) with at least one weight‑related health condition. When used alongside a reduced‑calorie meal plan and increased physical activity, Wegovy helps control appetite, reduce food cravings and support sustainable weight loss. Learn more about weight loss treatment options on our Weight Loss page.
Select Strength:
| Product Name: | Wegovy Pill |
|---|---|
| Manufacturer: | Novo Nordisk A/S |
| Active Ingredient: | Semaglutide |
| Administration: | Oral tablet, once daily |
| Presentation: | Tablets in alu/alu blister cards |
| Available Strengths: | 1.5 mg, 4 mg, 9 mg, 25 mg |
| Prescription Required: | Yes |
| Dosage: | Once daily (starting 1.5mg, titrating up to 25mg) |
| Suitable for pregnancy? | No (contraindicated) |
| Use with alcohol: | Not specifically restricted, but caution advised |
| Link to Patient Information Leaflet: | Wegovy Pill PIL |
| Strength | Package | Current Price |
|---|---|---|
| 1.5 mg | 30 tablets | £115.00 |
| 4 mg | 30 tablets | £120.00 |
| 9 mg | 30 tablets | £135.00 |
| 25 mg | 30 tablets | £180.00 |
| Wegovy Pill is a GLP-1 receptor agonist used for weight loss and weight maintenance. It belongs to the drug class GLP-1 analogues. Please consult with your healthcare provider before starting this medication. | ||
| This treatment requires an online consultation for review by our medical team. The decision to supply the specific treatment and quantity requested will be based on whether our medical team are satisfied that it will be safe, appropriate, and effective. | ||
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Table of Contents
- What is Wegovy Pill?
- What is Wegovy Pill Used For?
- Before Using Wegovy Pill
- Wegovy Pill Contraindications
- Special Population Considerations
- Wegovy Pill and Other Medicines
- Pregnancy & Breastfeeding
- Driving & Machine Operation
- Wegovy Pill Ingredients
- How to Use Wegovy Pill
- Wegovy Pill Dosage Guidelines
- Administration Instructions
- Missed Dose Management
- Overdose Information
- Wegovy Pill Side Effects
- How to Store Wegovy Pill
- Wegovy Pill Pack Information
- Wegovy Pill FAQs
What is Wegovy Pill?
Active ingredient and drug class
Wegovy Pill contains semaglutide, a medicine that belongs to a group of treatments known as GLP‑1 receptor agonists. It is manufactured by Novo Nordisk and is the first GLP‑1‑based weight‑loss treatment available in tablet form in the UK.
Mechanism of Action with Patient-Friendly Analogies
Think of GLP‑1 as your body's natural “fullness messenger.” After you eat, your gut releases this hormone to tell your brain that you have had enough food. Wegovy Pill works by mimicking this natural hormone, but it stays in your system for longer and acts more strongly.
More specifically, Semaglutide works by:
- Binding to GLP‑1 receptors in areas of the brain that regulate appetite and food intake
- This produces three key effects: reduced hunger, increased fullness, and reduced food cravings
- As a result, you naturally eat less food, which helps you lose weight and maintain that loss over time
Biological Pathway Explanation
Semaglutide binds to GLP‑1 receptors in areas of the brain that regulate appetite and food intake. This produces three key effects: Reduced hunger, Increased fullness, and Reduced food cravings. As a result, you naturally eat less food, which helps you lose weight and maintain that loss over time.
What is Wegovy Pill Used For?
Wegovy Pill is indicated for weight loss and weight maintenance, in addition to a reduced‑calorie diet and increased physical activity.
Approved Indications with Clinical Criteria
| Criterion | Details |
|---|---|
| Obesity | BMI of 30 kg/m² or greater |
| Overweight with weight‑related health problems | BMI of 27 kg/m² to less than 30 kg/m² AND at least one weight‑related comorbidity (e.g. type 2 diabetes, high blood pressure, dyslipidaemia, obstructive sleep apnoea) |
| Ethnicity‑adjusted BMI thresholds | Lower BMI thresholds (usually reduced by 2.5 kg/m²) apply for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African‑Caribbean backgrounds |
Target Patient Populations
Wegovy is intended for adults who have already tried lifestyle measures (diet and exercise) but have not achieved sufficient weight loss. It is not a quick fix or a standalone solution – it works best when combined with healthy eating, regular physical activity and long‑term behaviour change.
CRITICAL SAFETY WARNING
Do not take Wegovy Pill if you are allergic to semaglutide or any of the other ingredients.
Seek immediate medical help if you experience severe, persistent pain in your stomach area (abdomen) with or without nausea and vomiting – this could be a sign of acute pancreatitis, which is serious and potentially life‑threatening.
Urgently contact your doctor if you notice a sudden loss of vision or rapidly worsening eyesight – this may be a sign of non‑arteritic anterior ischaemic optic neuropathy (NAION).
Before Using Wegovy Pill
Before starting Wegovy Pill, a thorough medical assessment is essential to ensure safety and appropriateness.
Medical History Assessment Checklist
Your clinician will review the following conditions:
- Pancreatitis (inflammation of the pancreas)
- Kidney problems – dehydration from nausea, vomiting or diarrhoea can affect kidney function
- Diabetic eye disease (retinopathy) – rapid improvements in blood sugar control may temporarily worsen this condition
- Delayed stomach emptying (gastroparesis) – this may increase the risk of severe gastrointestinal side effects
- Gallstones – rapid weight loss can increase the risk of gallstone formation
Required Baseline Tests
- Blood tests to check kidney function, liver enzymes and pancreatic enzymes (lipase and amylase)
- Blood sugar monitoring if you have diabetes or are at risk of low blood sugar
- Eye examination if you have diabetic retinopathy
Pre-Treatment Evaluations
- BMI calculation to confirm eligibility
- Assessment of weight‑related comorbidities (blood pressure, cholesterol, blood sugar)
- Review of current medications to check for potential interactions
Wegovy Pill Contraindications
Contraindications are conditions that make Wegovy Pill treatment potentially harmful.
Absolute Contraindications (Do Not Use)
- Allergy to semaglutide or any of the other ingredients
- Pregnancy – should not be used during pregnancy
- Breast‑feeding – the medicine passes into breast milk
Relative Contraindications (Use with Caution)
- History of pancreatitis
- Diabetic retinopathy
- Gastroparesis
- Kidney impairment
- Sulfonylurea or insulin use
Special Population Considerations
Elderly Patients
Wegovy Pill can be used in older adults, but special attention should be paid to kidney function and risk of dehydration from gastrointestinal side effects. Dose adjustments are not specifically required based on age alone.
Renal Impairment
If you have kidney problems, you should be particularly careful to drink enough fluids to prevent dehydration, especially if you experience nausea, vomiting or diarrhoea. Your doctor may monitor your kidney function more closely.
Hepatic Impairment
No specific dose adjustment is required for patients with liver impairment. However, your doctor may monitor liver enzymes if you have pre‑existing liver disease.
Paediatric and Adolescent Restrictions
Wegovy Pill is not recommended for children and adolescents under 18 years of age, as the safety and effectiveness in this age group have not been established.
Wegovy Pill and Other Medicines
Wegovy Pill interacts with many medications. Always inform your doctor about ALL medicines you take, including prescription, OTC, and herbal supplements.
High-Risk Medication Combinations
| Medicine | Interaction | Action |
|---|---|---|
| Sulfonylureas (e.g. gliclazide, glimepiride) | Increased risk of low blood sugar (hypoglycaemia) | Your doctor may reduce the dose of your sulfonylurea |
| Insulin | Increased risk of low blood sugar (hypoglycaemia) | Your doctor may adjust your insulin dose |
| Warfarin / oral anticoagulants | May affect blood clotting | You may need more frequent blood tests to check how quickly your blood clots |
| Levothyroxine | May affect thyroid hormone levels | Your doctor may need to check your thyroid levels |
Timing Recommendations for Other Medications
Wegovy Pill must be taken on an empty stomach, and you must wait at least 30 minutes after taking it before eating, drinking or taking any other oral medicines. Taking other medicines or food within 30 minutes lowers the absorption of semaglutide.
Pregnancy & Breastfeeding
Clear Contraindication Statements
- Do not use Wegovy Pill during pregnancy. It is not known whether it affects your unborn baby.
- Do not use Wegovy Pill if you are breast‑feeding. The medicine passes into breast milk, and it is not known how it affects your baby.
Contraception Requirements
You must use contraception while taking Wegovy Pill. If you wish to become pregnant, discuss this with your doctor – you should stop using Wegovy Pill at least 2 months in advance of trying to conceive.
If You Become Pregnant While Taking Wegovy
Talk to your doctor straight away – your treatment will need to be changed.
Driving & Machine Operation
Impairment Potential Assessment
Wegovy Pill is unlikely to affect your ability to drive and use machines. However, some patients may feel dizzy – mainly during the first 3 months of treatment.
Warning Signs to Watch For
- If you feel dizzy, you should not drive or operate machines until you feel better.
- If you have diabetes and are taking Wegovy with a sulfonylurea or insulin, low blood sugar (hypoglycaemia) may occur, which can reduce your ability to concentrate.
- Do not drive or use machines if you get any signs of low blood sugar.
Wegovy Pill Ingredients
Active Ingredient
- Semaglutide – 1.5 mg, 4 mg, 9 mg or 25 mg per tablet
Other Ingredients (Excipients) and Their Functions
- Salcaprozate sodium – an absorption enhancer that helps semaglutide be absorbed through the stomach lining
- Magnesium stearate – a lubricant used in tablet manufacturing
Allergen Warnings
The 1.5 mg, 4 mg and 9 mg tablets contain less than 1 mmol sodium (23 mg) per tablet, meaning they are essentially sodium‑free. The 25 mg tablets contain 23 mg sodium per tablet, which is equivalent to 1% of the recommended maximum daily dietary intake of sodium for an adult.
How to Use Wegovy Pill
Step-by-Step Administration Guide
- Take on an empty stomach – after a recommended fasting period of at least 8 hours
- Swallow the tablet whole with a sip of water only (up to 120 mL) – do not split, crush or chew the tablet
- Wait at least 30 minutes after taking the tablet before eating, drinking or taking any other oral medicines
- Take once daily – preferably in the morning, to make it easier to remember
Important Reminders
- Do not take Wegovy tablets with any liquids other than water
- Waiting less than 30 minutes before eating or drinking lowers the absorption of semaglutide
- The tablet cannot be split or crushed – it is not known if this affects absorption of semaglutide
Wegovy Pill Dosage Guidelines
Titration Schedule
Your treatment will start at a low dose and be gradually increased over 4 months. Do not take two tablets to get the effect of a higher dose.
| Month | Dose | Frequency |
|---|---|---|
| Month 1 | 1.5 mg | Once daily |
| Month 2 | 4 mg | Once daily |
| Month 3 | 9 mg | Once daily |
| Month 4 and onward | 25 mg (maintenance dose) | Once daily |
Key Points
- The starting dose is 1.5 mg once daily for one month
- Each dose level should be taken for a minimum of one month
- Once you reach the recommended dose of 25 mg, do not increase this dose further
- Your doctor will assess your treatment on a regular basis
Transition from Wegovy Injection
Patients currently treated privately with a 2.4 mg semaglutide injection once weekly can be transitioned straight to semaglutide 25 mg tablets once daily
Administration Instructions
Detailed Step-by-Step Guide
- Fast for at least 8 hours – this means no food or drink (except water) during this time
- Take the tablet first thing in the morning with a small sip of water (no more than 120 mL)
- Swallow the tablet whole – do not split, crush or chew
- Set a timer for 30 minutes – do not eat, drink or take any other medicines during this time
- After 30 minutes, you can eat, drink and take your other medications as normal
What If I Have Type 2 Diabetes?
Tell your doctor if you have type 2 diabetes. Your doctor may adjust the dose of your diabetes medicines to prevent you from getting low blood sugar.
Missed Dose Management
Time-Based Guidance Table
| Scenario | Action |
|---|---|
| You forget to take a dose | Skip the missed dose and just take your normal dose the next day |
| You remember later in the day | Do not take a double dose – skip and continue as normal the next day |
Important: Do not take two tablets on the same day to make up for a missed dose.
Overdose Information
If You Take More Wegovy Than You Should
Talk to your doctor straight away. You may get side effects such as feeling sick (nausea).
Symptom Management
If you have taken more than the prescribed dose, you may experience:
- Nausea
- Vomiting
- Diarrhoea
- Stomach pain
- Dizziness
Seek medical advice if you experience severe or persistent symptoms.
Wegovy Pill Side Effects
Like all medicines, Wegovy Pill can cause side effects, although not everybody gets them.
Frequency-Based Categorization
Very Common (may affect more than 1 in 10 people)
- Headache
- Feeling sick (nausea)
- Being sick (vomiting)
- Diarrhoea
- Constipation
- Stomach pain
- Feeling weak or tired
- Upset stomach or indigestion
These usually go away over time as your body adjusts to the medicine.
Common (may affect up to 1 in 10 people)
- Feeling dizzy
- Burping
- Gas (flatulence)
- Bloating of the stomach
- Inflamed stomach (gastritis)
- Reflux or heartburn (gastro‑oesophageal reflux disease)
- Gallstones
- Hair loss
- Change in the way food or drink tastes
- Change in skin sensation
- Low blood sugar (hypoglycaemia) in patients with diabetes
Warning Signs of Low Blood Sugar (Hypoglycaemia)
The warning signs of low blood sugar may come on suddenly and can include:
- Cold sweat, cool pale skin
- Headache
- Fast heartbeat
- Feeling sick (nausea) or very hungry
- Changes in vision
- Feeling sleepy or weak
- Feeling nervous, anxious or confused
- Difficulty concentrating
- Shaking
Low blood sugar is more likely to happen if you also take a sulfonylurea or insulin. Your doctor may reduce your dose of these medicines before you start Wegovy.
Uncommon (may affect up to 1 in 100 people)
- Low blood pressure
- Feeling dizzy or lightheaded on standing or sitting up (drop in blood pressure)
- Fast heartbeat
- Increase of pancreatic enzymes (lipase and amylase) shown in blood tests
- A delay in the emptying of the stomach
- Low blood sugar (hypoglycaemia) in patients without diabetes
- Increased levels of bilirubin in your blood – signs include jaundice (yellowing of the skin or whites of the eyes)
Serious Side Effects – Seek Immediate Medical Help
| Frequency | Side effect | Action |
|---|---|---|
| Common | Complications of diabetic eye disease (diabetic retinopathy) | Tell your doctor |
| Uncommon | Inflamed pancreas (acute pancreatitis) – severe pain in the stomach and back that does not go away | Seek immediate medical help |
| Uncommon | Kidney or bladder stones | Tell your doctor |
| Rare | Severe allergic reactions (anaphylactic reactions, angioedema) | Seek immediate medical help |
| Rare | Hip fractures | Tell your doctor |
| Very rare | Non‑arteritic anterior ischaemic optic neuropathy (NAION) – painless loss of vision in one eye | Urgently contact your doctor |
| Not known | Bowel obstruction – severe constipation with stomach ache, bloating, vomiting | Tell your doctor |
Reporting of Side Effects
If you get any side effects, talk to your doctor, pharmacist or nurse. You can also report side effects directly via the Yellow Card Scheme at https://yellowcard.mhra.gov.uk/ or search for “MHRA Yellow Card” in the Google Play or Apple App Store.
How to Store Wegovy Pill
Temperature Requirements
- This medicine does not require any special temperature storage conditions
- Store in the original package to protect from light and moisture
Keep Out of Reach of Children
Keep this medicine out of the sight and reach of children.
Expiry Date
Do not use this medicine after the expiry date stated on the blister and carton after “EXP”. The expiry date refers to the last day of that month.
Disposal
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use.
Wegovy Pill Pack Information
Tablet Appearance
| Strength | Description | Markings |
|---|---|---|
| 1.5 mg | White to light yellow, round (6.5 mm diameter) | “1.5” on one side, “novo” on the other |
| 4 mg | White to light yellow, round (6.5 mm diameter) | “4” on one side, “novo” on the other |
| 9 mg | White to light yellow, round (6.5 mm diameter) | “9” on one side, “novo” on the other |
| 25 mg | White to light yellow, oval (6.8 mm × 12 mm) | “25” on one side, “novo” on the other |
Pack Sizes
The 1.5 mg, 4 mg, 9 mg and 25 mg tablets are available in alu/alu blister cards in pack sizes of 10, 30 and 90 tablets.
Not all pack sizes may be marketed in your country.
Marketing Authorisation Holder
Novo Nordisk A/S, Novo Alle, DK‑2880 Bagsvær, Denmark
Where Can I Buy Wegovy Pill Online in the UK
Secure Wegovy Pill Prescription & Next-Day Delivery Service
Order Wegovy Pill with confidence through our UK-registered medical prescribers, who review all requests within 4 working hours. We guarantee same-day prescription approval for eligible patients and dispatch orders placed before 3pm for next-day tracked delivery.
Our Wegovy Pill service combines competitive pricing with strict adherence to MHRA safety standards, ensuring your medication is dispensed through GPhC-registered pharmacies. Every purchase includes discreet packaging and a GDPR-compliant consultation process.
Our clinical team ensures:
- Comprehensive medical history review
- Weight loss eligibility assessment
- Drug interaction checks
- Personalised dosing and titration guidance
Always consult your GP before starting GLP-1 agonist treatment. Not recommended for long-term use without medical supervision.
Wegovy Pill FAQs
What is the Wegovy Pill?
The Wegovy Pill is a once‑daily tablet containing semaglutide, a GLP‑1 receptor agonist used for weight loss and weight maintenance in adults with obesity or overweight with weight‑related health problems.
How does the Wegovy Pill work?
It works by mimicking the natural hormone GLP‑1, which is released after eating. It acts on areas of the brain that regulate appetite, helping you feel fuller for longer, reducing hunger and decreasing food cravings.
What is the difference between Wegovy Pill and Wegovy injection?
The Wegovy Pill is taken once daily as an oral tablet, while the Wegovy injection is given once weekly. Both contain the same active ingredient (semaglutide) and work in the same way. The pill offers a needle‑free alternative and does not require refrigeration.
Who is eligible for the Wegovy Pill?
Adults with a BMI of 30 kg/m² or greater (obesity), or a BMI of 27 to less than 30 kg/m² (overweight) with at least one weight‑related health problem. Lower BMI thresholds apply for certain ethnic groups.
What is the starting dose of Wegovy Pill?
The starting dose is 1.5 mg once daily for one month. The dose is then increased to 4 mg, 9 mg and finally 25 mg, with a minimum of one month at each dose level.
How should I take Wegovy Pill?
Take it on an empty stomach after fasting for at least 8 hours. Swallow the tablet whole with a sip of water (up to 120 mL) and wait at least 30 minutes before eating, drinking or taking other medicines.
Can I take Wegovy Pill with other medications?
Yes, but tell your doctor about all medicines you are taking. Special caution is needed with sulfonylureas, insulin, warfarin and levothyroxine. You must wait 30 minutes after taking Wegovy before taking other oral medicines.
Is Wegovy Pill safe during pregnancy?
No. Wegovy Pill should not be used during pregnancy. You must use contraception while taking it and stop at least 2 months before trying to conceive.
Can I take Wegovy Pill while breast‑feeding?
No. Wegovy Pill passes into breast milk, and it is not known how it affects your baby.
What are the most common side effects of Wegovy Pill?
The most common side effects are gastrointestinal – nausea, vomiting, diarrhoea, constipation, stomach pain and indigestion. These usually improve over time.
Can Wegovy Pill cause low blood sugar?
Yes, especially if you also take a sulfonylurea or insulin. Warning signs include cold sweat, pale skin, headache, fast heartbeat, nausea, vision changes, sleepiness, nervousness and shaking.
What should I do if I miss a dose?
Skip the missed dose and take your normal dose the next day. Do not take two tablets on the same day.
Is the Wegovy Pill available on the NHS?
Currently, the Wegovy Pill is approved for use in the UK but is not available via the NHS. Most patients access it through private online pharmacies and specialist weight management providers.
How much does the Wegovy Pill cost?
Prices vary by provider. Typical monthly costs range from £115 to £180 depending on the dose and provider.
How long does it take to see results with Wegovy Pill?
In clinical trials, patients taking semaglutide 25 mg achieved approximately 14–17% weight loss after 64 weeks. Individual results vary, and weight loss is gradual.
Sources
Medical Content Manager
Nabeel is a co-founder, and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.
Medical Doctor
Dr. Talal is a GMC registered doctor and medical reviewer at Chemist Doctor. He ensures clinical accuracy and reliability across health content.
Medical Director
Usman is a co-founder, and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.
Review Date: 08 Jul 2026
Next Review: 08 Jan 2027
Published on: 08 Jul 2026
Last Updated: 08 Jul 2026
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