Question 1

How quickly does Lariam start working after a dose?

Accepted Answer

Lariam reaches peak blood levels 6–24 hours after a dose. For prevention, it's essential to start 10 days before travel to ensure protective levels are present when you enter a malaria area.

Question 2

Can Lariam cause long-term side effects?

Accepted Answer

In a small number of people, dizziness, balance problems, or depression may persist for months or longer after stopping Lariam. Seek medical advice if symptoms continue.

Question 3

Does Lariam work against all types of malaria?

Accepted Answer

Lariam is effective against P. falciparum, P. vivax, P. ovale, and P. malariae. However, it does not prevent relapses of P. vivax or P. ovale; additional treatment may be needed.

Question 4

Why is Lariam taken only once a week?

Accepted Answer

Lariam has an exceptionally long half-life of 2–3 weeks. Once-weekly dosing maintains continuous protective levels in the blood, making it convenient for long-term travellers.

Question 5

Can I drink alcohol while taking Lariam?

Accepted Answer

Moderate alcohol is not known to interact with Lariam directly, but both can affect the liver and cause dizziness. It's best to limit alcohol, especially if you experience any neuropsychiatric symptoms.