Question 1

Why take it for 7 days after return?

Accepted Answer

The long half‑life of atovaquone means that after the last dose, protective levels remain for several days. The 7‑day course ensures any parasites that emerged from the liver during travel are exposed to the drug and killed.

Question 2

How quickly does Malarone start working?

Accepted Answer

Malarone reaches effective blood levels within a few hours after the first dose, but you must start 1‑2 days before travel to ensure protection from day one in the malaria area.

Question 3

Can Malarone cure malaria completely?

Accepted Answer

Yes, when taken correctly (3‑day course) it cures uncomplicated P. falciparum malaria in >95% of cases. It also kills liver stages, preventing relapse.

Question 4

Why must I take Malarone with food?

Accepted Answer

Food, especially fat, increases atovaquone absorption by up to 100%. Without food, levels may be too low to prevent malaria.

Question 5

Does Malarone affect the liver?

Accepted Answer

In rare cases, transient liver enzyme elevations have been reported. Severe hepatitis is very rare. Regular monitoring is not needed unless you have pre‑existing liver disease.

Question 6

What happens if I vomit after taking Malarone?

Accepted Answer

If vomiting occurs within 1 hour of a dose, take another full dose. If vomiting persists, contact your doctor – you may need a different antimalarial.