How Does Proctosedyl Work: Mechanism of Action & Metabolic Effects
Table of Contents
Key Takeaways
- Mechanism: Hydrocortisone reduces inflammation; cinchocaine numbs pain.
- For: Adults (12+ years) with haemorrhoids/anal fissures.
- Avoid if: Allergic to ingredients, active infections (e.g., herpes), tuberculosis, or under 12 years.
- Dosage: Apply 3x daily for 1 week, then reduce gradually (max 3 weeks).
- Warning: Prolonged use may cause skin thinning or adrenal suppression.
This comprehensive guide examines how Proctosedyl ointment works for haemorrhoid relief, detailing its unique triple action mechanism combining hydrocortisone's anti-inflammatory properties, cinchocaine's local anaesthetic effects, and a protective barrier. We'll explore how Proctosedyl targets pain, swelling and irritation simultaneously, explain why its topical application provides direct relief where needed, and reveal what patients can realistically expect from this multi-symptom treatment.
How Proctosedyl Ointment Works
Proctosedyl’s dual-action formula targets both inflammation and pain:
Hydrocortisone (5mg/g)
- Action: Corticosteroid that inhibits inflammatory chemicals (prostaglandins, leukotrienes)
- Effect: Reduces swelling, redness, and itching
Cinchocaine (5mg/g)
- Action: Local anaesthetic blocks nerve signals
- Effect: Numbs pain within 5-10 minutes of application
Note: Proctosedyl does not treat infections or shrink haemorrhoids permanently. It provides symptomatic relief.
Who Can Use Proctosedyl Ointment?
Suitable For:
- Adults and adolescents (12+ years) with symptomatic haemorrhoids or anal fissures
- Patients with mild to moderate pain/swelling
- Those without allergies to ingredients (see contraindications)
Special Populations
| Group | Recommendation |
|---|---|
| Pregnant/Breastfeeding | Use only if prescribed by a doctor |
| Elderly | Monitor for skin thinning (higher risk) |
| Diabetes | May need closer glucose monitoring (steroids can raise blood sugar) |
Who Should Avoid Proctosedyl Ointment?
Medical Conditions
- Active infections (bacterial, viral like herpes, fungal, or parasitic)
- Tuberculosis (may worsen with steroids)
- Perianal thrush (requires antifungal treatment first)
- Undiagnosed rectal bleeding (could indicate serious conditions like cancer)
Allergies & Sensitivities
- Hypersensitivity to hydrocortisone, cinchocaine, or wool fat/paraffin
- History of allergic contact dermatitis to topical steroids
Other Groups
- Children under 12 (safety not established)
- Patients using latex condoms (potential interaction)
FAQs
Can Proctosedyl cure haemorrhoids?
No. It relieves symptoms but doesn't treat the underlying cause. Lifestyle changes (high-fibre diet, hydration) are needed to prevent recurrence.
Can I use Proctosedyl with other haemorrhoid treatments?
Yes (e.g., fibre supplements), but avoid other steroid creams unless prescribed. Space applications by 30 minutes if using multiple topicals.
Why can't children under 12 use Proctosedyl?
Their skin absorbs steroids more easily, increasing risks of adrenal suppression and systemic side effects.
 | Authored by Nabeel |
Medical Content Manager
Nabeel is a co-founder, and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.
 | Reviewed by Dr. Waqas (GMC:7928708) |
Medical Doctor
Dr. Waqas is a GMC-registered doctor at Chemist Doctor, specialising in general health. He balances clinical precision with cultural sensitivity.
 | Approved by Usman |
Medical Director
Usman is a co-founder, and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.
Review Date: 12 August 2025
Next Review: 14 February 2026
Published on: 11 August 2025
Last Updated: 12 August 2025
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