How To Take Fexofenadine: Step-by-Step Dosage Guide
Key Takeaways
- Dosage: 1 tablet (120mg) daily with water before food
- Timing: Works within 1 hour; lasts 24 hours
- Avoid: Fruit juices and antacids within 2 hours
- Consistency: Take at the same time daily for best results
- Safety: Non-drowsy for most users (check individual response)
Proper administration of fexofenadine tablets ensures optimal allergy relief while minimizing potential side effects. Our visual guide demonstrates correct dosage techniques for adults and children, explains crucial food interactions (particularly fruit juices that may reduce absorption), and provides timing recommendations for both preventive and symptomatic use.
Dosage Instructions
- Standard dose:
- Adults and adolescents (12+ years): 1 tablet (120mg) once daily
- Do not exceed the recommended dose
- Special cases:
- Kidney impairment (eGFR 30-80 mL/min): Consider 60mg daily
- Severe kidney impairment (eGFR <30 mL/min): Avoid or use under medical supervision
When to Take Fexofenadine
Best practice: Take at the same time each day (e.g., with breakfast) to maintain consistent blood levels.
Optimal Timing
- Before meals: Take with water 30 minutes before food for best absorption
- For seasonal allergies: Start taking 1-2 weeks before pollen season begins
- For year-round allergies: Continue daily use as prescribed
How to Take the Tablet
- Swallow whole: Do not crush, chew, or break the tablet
- With water: Take with a full glass of water (avoid fruit juices)
- Position: Sit or stand upright when swallowing
- Follow with: Remain upright for 30 minutes after taking
Note: The tablet has a film coating to make swallowing easier and mask the taste.
Important Interactions
What to Avoid
| Substance | Interaction | Recommendation |
|---|---|---|
| Fruit juices (apple, orange, grapefruit) | Reduce absorption by 30-40% | Take with water only |
| Antacids (aluminium/magnesium) | Decrease effectiveness | Separate by 2 hours |
| Apalutamide (prostate cancer drug) | May reduce efficacy | Consult your doctor |
FAQs
Can I take Fexofenadine at night?
What if I vomit after taking a tablet?
Can children take Fexofenadine 120mg?
How long can I safely use Fexofenadine?
Does Fexofenadine work better with food?
Can I take Fexofenadine with alcohol?
Why should I avoid fruit juice with Fexofenadine?
Can I take 2 tablets (240mg) for worse symptoms?
 | Authored by Nabeel |
Medical Content Manager
Nabeel is a co-founder, and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.
 | Reviewed by Dr. Waqas (GMC:7928708) |
Medical Doctor
Dr. Waqas is a GMC-registered doctor at Chemist Doctor, specialising in general health. He balances clinical precision with cultural sensitivity.
 | Approved by Usman |
Medical Director
Usman is a co-founder, and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.
Review Date: 12 August 2025
Next Review: 14 February 2026
Published on: 11 August 2025
Last Updated: 12 August 2025
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