How to Use Circadin (Melatonin) Tablets Correctly
A step-by-step guide to taking Circadin 2mg prolonged-release melatonin for insomnia in adults aged 55+.
Key Takeaways
- Dosage: 1 tablet (2mg) taken 1-2 hours before bedtime
- Administration: Swallow whole with water - do not crush/chew
- Timing: Take at same time nightly for circadian rhythm regulation
- Duration: Maximum 13 weeks continuous use
- Avoid: Food for 2 hours after dosing; alcohol entirely
Circadin provides targeted sleep support through its prolonged-release melatonin formulation, helping regulate the sleep-wake cycle in adults over 55.
Dosage Instructions
- Standard dose:
- Adults 55+: 1 tablet (2mg) once daily
- Do not exceed recommended dose
- Special cases:
- Liver impairment: Start with 1mg (half tablet) if severe
- Epilepsy: Monitor for increased seizure frequency
Optimal Timing
Best practice: Take 1-2 hours before desired bedtime to align with natural melatonin release.
Why This Timing Matters
- 1 hour before: Allows melatonin levels to rise before sleep attempt
- 2 hours after sunset: Mimics natural circadian rhythm in older adults
- Consistent timing: Regulates the body's internal clock more effectively
Food Interactions
| Food/Drink | Recommendation |
|---|---|
| Evening meal | Finish ≥2 hours before Circadin |
| Caffeine | Avoid after 2pm |
| Alcohol | Contraindicated (reduces effectiveness) |
How to Take the Tablet
- Swallow whole: Do not crush, chew, or break the prolonged-release tablet
- With water: Take with a full glass (200ml) of water
- Position: Sit upright for 30 minutes after taking
- Environment: Take in low-light conditions to enhance melatonin effects
Pro tip: Combine with good sleep hygiene - dark, cool room and no screens before bed.
Duration of Treatment
Recommended Course
- Initial trial: 3 weeks minimum to assess effectiveness
- Maximum continuous use: 13 weeks
- Long-term management: Intermittent use (e.g., 3-5 nights/week)
When to Reassess
| Situation | Action |
|---|---|
| No improvement after 3 weeks | Consult GP for alternative treatments |
| Side effects persist | Consider dose reduction or discontinuation |
| Sleep patterns stabilize | Gradually taper use (e.g., alternate nights) |
Frequently Asked Questions
Can I cut Circadin tablets in half?
No. The prolonged-release coating will be damaged. For lower doses, consult your doctor about liquid melatonin.
What if I wake up during the night after taking Circadin?
Avoid taking another dose. The 2mg formulation provides all-night coverage. Practice relaxation techniques instead.
Why must I avoid food after taking Circadin?
Food delays absorption by 1-2 hours, reducing effectiveness. Fasting ensures optimal release timing.
Can I use Circadin for jet lag?
Yes, but timing differs: Take at local bedtime starting 1-2 days before travel and continue 2-5 days after arrival.
Is morning drowsiness normal with Circadin?
Mild drowsiness affects ~10% of users. If persistent, take earlier in the evening or reduce to 1mg (under medical supervision).
Need Treatment for Jet Lag
If you're experiencing sleep difficulties, our UK-registered doctors can help determine if Circadin (Melatonin) Tablets is appropriate for your condition through a confidential online consultation.
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Medical Content Manager
Nabeel is a co-founder and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.
Medical Doctor
Dr. Feroz is a GMC-registered doctor and a medical reviewer at Chemist Doctor. He oversees acute condition and urgent care guidance.
Medical Director
Usman is a co-founder and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.
Review Date: 29 October 2025
Next Review: 30 April 2026
Published on: 29 October 2025
Last Updated: 30 October 2025
