Acnecide Gel


Acnecide 5% w/w Gel tube - 30g size
Acnecide 5% w/w Gel

Acnecide 5% w/w Gel contains benzoyl peroxide, a prescription topical treatment for mild to moderate acne on the face, chest, and back. This medication is available through Chemist Doctor's regulated online service following a consultation with UK-licensed clinicians.

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What is Acnecide?

Acnecide 5% w/w Gel is a prescription topical medication containing the active substance benzoyl peroxide. It belongs to a class of medicines called topical antimicrobials and keratolytics, specifically formulated for the treatment of acne vulgaris.

Mechanism of Action

Benzoyl peroxide works through three primary mechanisms:

  • Antibacterial Action: Releases free oxygen radicals that kill Cutibacterium acnes, the bacteria primarily responsible for acne inflammation
  • Keratolytic Effect: Helps unclog pores by promoting the shedding of dead skin cells from the follicle lining
  • Anti-inflammatory Properties: Reduces inflammation in existing acne lesions, decreasing redness and swelling

Imagine your pores as small tubes that can get clogged with oil and dead skin cells. Acnecide acts like a gentle cleaner that kills harmful bacteria, unclogs blockages, and calms irritated skin.

What is Acnecide Used For?

Acnecide Gel is indicated for the topical treatment of mild to moderate acne vulgaris on the:

  • Face
  • Chest
  • Back

Approved Indications

Acne TypeClinical PresentationTarget Areas
Inflammatory acne Papules, pustules, mild cysts Face, chest, back
Comedonal acne Blackheads, whiteheads Face, chest, back
Mixed acne lesions Combination of inflammatory and non-inflammatory lesions Face, chest, back

Important Safety Notice:

Discontinue immediately and seek medical help if you experience:

  • Severe allergic reaction (difficulty breathing, facial swelling)
  • Severe skin irritation, blistering, or peeling
  • Accidental ingestion - seek immediate medical attention

Before Using Acnecide

Essential considerations before initiating treatment:

Medical History Assessment

  • History of hypersensitivity or allergic reactions to benzoyl peroxide
  • Known allergies to medications, cosmetics, or skincare products
  • History of eczema, dermatitis, or chronic skin conditions
  • Previous adverse reactions to topical acne treatments

Required Baseline Assessments

  1. Skin type assessment (sensitive, dry, oily, combination)
  2. Current skincare regimen review
  3. Acne severity assessment
  4. Review of current medications (prescription and over-the-counter)

Acnecide Contraindications

Absolute contraindications where Acnecide must not be used:

Absolute Contraindications

  • Hypersensitivity to benzoyl peroxide or any component of the formulation
  • History of severe allergic reaction (angioedema, anaphylaxis) to peroxide compounds

Relative Contraindications (Use with caution)

  • Severely inflamed or broken skin in treatment area
  • Active eczema or dermatitis in areas to be treated
  • History of contact dermatitis with topical products
  • Concurrent use of other topical acne medications (unless advised by clinician)

Special Population Considerations

Elderly Patients (65+ years)

  • Limited specific data exists
  • Elderly skin may be more fragile - start with lower frequency
  • Monitor closely for excessive dryness or irritation

Pediatric/Adolescent Patients

  • Commonly prescribed for adolescents (typically ages 12+)
  • Ensure proper application technique is understood
  • Monitor for excessive dryness which may lead to non-compliance

Renal or Hepatic Impairment

  • No specific dosage adjustments needed
  • Minimal systemic absorption when applied topically as directed

Acnecide and Other Medicines

Significant interactions requiring monitoring:

High-Risk Combinations

  • Other topical acne treatments (retinoids, salicylic acid): Increased skin irritation, dryness, peeling
  • Topical tretinoin: Benzoyl peroxide may inactivate tretinoin - apply at different times

Timing Recommendations

  • If using multiple topical products, space applications by 1-2 hours
  • Apply Acnecide after cleansing and before moisturizing
  • Avoid applying other topical medications to same area simultaneously

Pregnancy & Breastfeeding

Pregnancy

  • Limited data on benzoyl peroxide use in pregnancy
  • Avoid use unless deemed essential by your doctor
  • If used during pregnancy, apply minimum amount necessary

Breastfeeding

  • Not recommended during breastfeeding
  • If use is medically necessary, do NOT apply to chest area
  • Wash hands thoroughly after application

Driving & Machine Operation

  • No known effects on ability to drive or operate machinery
  • Benzoyl peroxide is minimally absorbed systemically
  • If accidentally gets into eyes, may cause temporary irritation or blurred vision
  • Do not drive or operate machinery until vision clears completely if eye contact occurs

Acnecide Ingredients

Active Substance

  • Benzoyl Peroxide: 5% w/w

Excipients

IngredientFunctionAllergen Notes
Docusate sodiumSurfactantGenerally well-tolerated
Disodium edetateChelating agentLow allergenic potential
Poloxamer 182EmulsifierRarely causes reactions
Carbomer 940Gelling agentMay cause irritation in sensitive individuals
Propylene glycolHumectantMay cause skin irritation (40 mg per gram)
Purified waterVehicle/baseNon-allergenic

How to Use Acnecide Gel

Preparation Steps

  1. Wash affected area with mild, non-medicated cleanser and lukewarm water
  2. Pat dry gently with clean towel
  3. Ensure hands are clean before handling tube

Application Technique

  • Amount: Pea-sized amount (approx. 0.5g) for entire face
  • Apply: Thin layer to all affected areas
  • Avoid: Eyes, mouth, angles of nose, mucous membranes
  • Massage: Gently massage into skin until absorbed

Post-Application Protocol

  1. Wash hands thoroughly after application
  2. Wait 5-10 minutes for gel to absorb
  3. Apply non-comedogenic moisturizer if needed

Acnecide Dosage Guidelines

Standard Application Schedule

Treatment WeekFrequencyApplication TimeExpected Effects
Weeks 1-2Once dailyEvening (or morning if preferred)Initial dryness, mild peeling possible
Weeks 3-4Once or twice dailyMorning and/or eveningReduced inflammation, fewer new lesions
Weeks 5-8Twice daily (if tolerated)Morning and eveningContinued improvement, skin adjustment
Maintenance (after 8 weeks)Once daily or as neededEvening usually sufficientMaintained clearance, prevention of new lesions

Application Frequency by Skin Type

  • Normal/Oily skin: Start once daily, increase to twice daily after 1-2 weeks
  • Sensitive/Dry skin: Start once every other day, increase to once daily after 2-3 weeks
  • Very sensitive skin: Start once every 2-3 days, gradually increase as tolerated

Administration Instructions

Step-by-step application guide:

Amount Guidelines

  • Face: Pea-sized amount (approx. 0.5g)
  • Chest: Blueberry-sized amount (approx. 1g)
  • Back: Two pea-sized amounts (approx. 1g total)

Areas to Avoid

  • Eyes and eyelids
  • Lips and mouth
  • Inside nostrils
  • Broken or damaged skin
  • Areas with cuts, abrasions, or sunburn

Sun Protection

Benzoyl peroxide may increase sun sensitivity. Apply sunscreen (SPF 30+) every morning when using Acnecide.

Missed Dose Management

General Principles

  • Do NOT apply extra gel to make up for missed dose
  • Consistency is important but occasional missed doses won't significantly affect treatment

Time-Based Guidance

Time Since Missed DoseAction
Less than 3 hoursApply as soon as remembered, then continue with next dose at regular time
More than 3 hoursSkip missed dose, continue with next dose at regular time
Near next dose timeSkip missed dose entirely

Overdose Information

Topical Overapplication

  • Symptoms: Increased redness, irritation, burning, stinging, peeling, dryness
  • Management: Wash off excess gel, allow skin to recover 1-2 days, restart with less frequent application

Accidental Ingestion

EMERGENCY: If Acnecide gel is accidentally swallowed, seek immediate medical attention. Do not induce vomiting unless instructed by medical personnel.

First Aid Measures:

  1. Do NOT induce vomiting
  2. Rinse mouth with water
  3. Drink glass of water or milk (unless unconscious)
  4. Seek immediate medical attention
  5. Bring medication package to hospital

Possible Side Effects

Very Common (more than 1 in 10 people)

  • Dry skin
  • Skin redness (erythema)
  • Peeling of the skin
  • Burning sensation

Common (1 in 10 to 1 in 100 people)

  • Itching (pruritus)
  • Skin pain/stinging
  • Irritation (irritant contact dermatitis)

Serious Side Effects

EffectFrequencyAction Required
Severe Allergic ReactionRareDISCONTINUE immediately, emergency treatment
Severe Skin ReactionRareDISCONTINUE, medical evaluation
Eye Damage SymptomsRareEmergency medical attention

Managing Common Side Effects

  • Dryness/Peeling: Use non-comedogenic moisturizer, reduce application frequency
  • Redness: Apply less gel, use every other day, avoid sun exposure
  • Burning/Stinging: Apply to completely dry skin, reduce amount used

How to Store Acnecide

Storage Conditions

  • Do not store above 25°C
  • Do not freeze
  • Store in original tube away from direct heat and sunlight
  • Keep tube tightly closed when not in use

Shelf Life and Expiry

  • Do not use after expiry date printed on tube and carton
  • Typical shelf life: 2-3 years from manufacturing date

Disposal

  • Do not throw away via wastewater or household waste
  • Return to pharmacy for safe disposal
  • Follow specific disposal instructions from pharmacist

Pack Information

Pack Sizes

  • 15g tube
  • 30g tube
  • 60g tube

Components

  • One tube of Acnecide 5% w/w Gel
  • Patient information leaflet
  • Cardboard outer carton

Appearance

  • White to off-white aqueous gel
  • Aluminium tube packaging

Where Can I Buy Acnecide Online in the UK

Secure Acnecide Prescription & Next-Day Delivery Service

Order Acnecide with confidence through our UK-registered medical prescribers, who review all requests within 4 working hours. We guarantee same-day prescription approval for eligible patients and dispatch orders placed before 3pm for next-day tracked delivery.

Our Acnecide service combines competitive pricing with strict adherence to MHRA safety standards, ensuring your medication is dispensed through GPhC-registered pharmacies. Every purchase includes discreet packaging and a GDPR-compliant consultation process.

Our clinical team ensures:

  • Comprehensive skin assessment and medical history review
  • Acne type and severity evaluation
  • Drug interaction checks with current medications
  • Personalised application guidance and skincare advice

Always consult your GP before starting acne treatment. Not recommended for children under 12 or those with known benzoyl peroxide allergy.

Acnecide (Benzoyl Peroxide) FAQs

Most people see improvement within 2-4 weeks of regular use:

  • Optimal results typically visible after 8-12 weeks
  • Initial results include reduced inflammation and fewer new spots
  • Complete clearance of existing lesions may take longer
  • Continue treatment as prescribed even if immediate results aren't apparent

Yes, using a non-comedogenic, oil-free moisturizer is recommended:

  • Apply Acnecide first, wait 5-10 minutes for absorption
  • Then apply moisturizer
  • Look for products labeled "non-comedogenic" or "oil-free"
  • Moisturizers help manage dryness and peeling side effects

Some people experience an initial "purge" during first 2-4 weeks:

  • Occurs as benzoyl peroxide accelerates skin cell turnover
  • Brings underlying impurities to surface more quickly
  • Temporary effect indicating medication is working
  • Consult doctor if severe worsening persists beyond 4 weeks

Acnecide can be used on sensitive skin with proper precautions:

  1. Start with application every 2-3 days
  2. Gradually increase frequency as tolerated
  3. Use smaller amount and apply to completely dry skin
  4. If irritation occurs, reduce frequency or take 1-2 day break
  5. Those with very sensitive skin or rosacea should consult doctor first

Yes, but follow these guidelines:

  • Wait 5-10 minutes after applying Acnecide
  • Choose oil-free, non-comedogenic makeup products
  • Mineral-based makeup often works well for acne-prone skin
  • Always remove makeup thoroughly before reapplying Acnecide or bedtime

Yes, Acnecide is approved for treating acne on:

  • Chest
  • Back
  • Other affected body areas

Use slightly larger amount for body areas (approx. 1g for chest, 1g for back). Body skin may be less sensitive but still start with once-daily application.

Benzoyl peroxide can increase sun sensitivity:

  • Always apply broad-spectrum sunscreen SPF 30+ every morning
  • Avoid excessive sun exposure and tanning beds
  • Wear protective clothing during extended sun exposure
  • Reapply sunscreen every 2 hours if in direct sunlight

Combination therapy requires medical supervision:

  • Can be combined with certain treatments (like topical retinoids or oral antibiotics)
  • Should not be used simultaneously with other topicals without doctor approval
  • If using multiple products, apply at different times (e.g., Acnecide morning, retinoid night)
  • Excessive combination may cause irritation

Continue as recommended by your doctor:

  • Typically several months for initial treatment
  • Acne often requires ongoing maintenance therapy
  • Many use long-term at reduced frequency (once every other day)
  • Do not stop suddenly if acne has improved - may lead to recurrence

If irritation occurs:

  1. Reduce application frequency to every other day or every 2-3 days
  2. Use smaller amount
  3. Apply to completely dry skin (wait 20-30 minutes after washing)
  4. Use gentle, fragrance-free moisturizer
  5. Avoid other potentially irritating products
  6. If severe or persistent, stop using and consult doctor

Yes, effective against both:

  • Inflammatory lesions (red spots)
  • Non-inflammatory comedones (blackheads and whiteheads)
  • Keratolytic action helps unclog pores and prevent new comedones
  • For primarily comedonal acne, doctor might recommend combination with retinoid

Benzoyl peroxide has been used safely for decades:

  • Long-term studies support safety for extended use
  • Periodic review with doctor recommended
  • Some may need to adjust frequency over time
  • No known cumulative toxic effects from long-term topical use when applied as directed
Medical Content Manager
Authored by Nabeel

Medical Content Manager

Nabeel is a co-founder, and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.

Medical Doctor

Dr. Talal is a GMC registered doctor and medical reviewer at Chemist Doctor. He ensures clinical accuracy and reliability across health content.

Medical Director
Approved by Usman

Medical Director

Usman is a co-founder, and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.

Review Date: 01 January 2026

Next Review: 01 July 2026

Published on: 01 January 2026

Last Updated: 01 January 2026

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4.5 ★★★★★

Based on verified customer reviews

Sarah, 24 ★★★★☆

"After struggling with acne for years, Acnecide has really helped clear my skin. The online consultation was straightforward and the delivery was quick. It did cause some dryness at first, but that improved after a few weeks."

Verified purchase · October 2023
James, 19 ★★★★★

"The service was discreet and professional. Acnecide has reduced my breakouts significantly. I appreciate not having to visit a GP surgery for a prescription."

Verified purchase · September 2023
Emma, 29 ★★★☆☆

"Effective for spots but quite drying. The convenience of home delivery is great, but I needed to use a good moisturizer alongside it. Customer service was helpful when I had questions."

Verified purchase · August 2023

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