How To Use Flixonase

Complete Step-by-Step Usage Guide, Dosage Instructions & Safety Information

Key Takeaways: Using Flixonase Correctly

  • Prime new spray: Pump a few times until a fine mist appears before first use or if not used for a few days.
  • Daily routine: Use at the same time each day, preferably in the morning. Shake gently before each use.
  • Dosage: Adults: 2 sprays each nostril once daily (max 8 sprays/day). Children 4‑11: 1 spray each nostril once daily (max 4 sprays/day).
  • Cleaning: Wipe nozzle daily; deep clean weekly by soaking nozzle and cap in warm water.
  • Persistence: Benefits build over a few days – keep using even if you don't feel immediate relief.

Flixonase (fluticasone propionate) nasal spray is a prescription medicine for preventing and treating allergic rhinitis. Using it correctly ensures the medicine reaches the nasal lining and works effectively. Below is a detailed step‑by‑step guide based on the official Patient Information Leaflet.

Important Safety Advice

If you accidentally spray into your eyes, rinse immediately with cold water. Seek medical help if you experience sudden wheezing, swelling of the face or mouth, or severe skin rash – these could be signs of an allergic reaction. Consult your doctor if symptoms do not improve after 7 days of regular use.

How to Take Flixonase: Step-by-Step Usage Guide

Follow these steps carefully to get the full benefit of your medicine. The illustrations in the PIL can help, but the verbal steps are summarised here.

  1. Prepare the spray: If using a new bottle or one not used for a few days, you need to prime it. Shake the bottle gently, remove the dust cap, hold it with your thumb at the bottom and index/middle fingers on the white collar. Point away from you and press down firmly a few times until a fine mist appears.
  2. Clear your nose: Gently blow your nose to remove any mucus.
  3. Position the bottle: Close one nostril with a finger. Tilt your head forward slightly and insert the nozzle into the other nostril. Keep the bottle upright – do not tilt it.
  4. Administer the spray: Start to breathe in slowly through your nose. While breathing in, press down firmly on the collar to release one spray. Breathe out through your mouth.
  5. Repeat if needed: If your prescribed dose is two sprays in that nostril, repeat step 4. Then move to the other nostril and repeat steps 3‑5.
  6. After use: Wipe the nozzle with a clean tissue and replace the dust cap.
  7. Weekly cleaning: Remove the nozzle by pulling upwards (do not twist). Soak the nozzle and dust cap in warm water for a few minutes, rinse, shake off excess, and let them dry in a warm place. Reattach and re‑prime (one spray into the air) before next use.

🗒️ Pro tip: To avoid getting spray in your eyes, keep your head tilted forward slightly and look downwards during administration.

Dosage Guide for Adults and Children

Always use Flixonase exactly as your doctor or pharmacist has told you. The usual doses are:

Age groupUsual starting doseMaximum dose in 24 hours
Adults and children ≥12 years2 sprays into each nostril once daily (preferably morning)4 sprays into each nostril (8 sprays total)
Children 4‑11 years1 spray into each nostril once daily (preferably morning)2 sprays into each nostril (4 sprays total)
Children under 4 yearsNot recommended (safety not established)

Missed dose: If you forget a dose, just take the next dose at the usual time. Do not take a double dose to make up for a missed one.

If you use more than you should: Tell your doctor. Using too much for a long time might affect your body's natural steroid production, but this is very unlikely with nasal spray because absorption is minimal.

Who Should Use Flixonase

Flixonase is suitable for adults and children aged 4 years and older who need prevention or treatment of:

  • Seasonal allergic rhinitis (hayfever) – caused by pollen from grass, trees, or weeds.
  • Perennial allergic rhinitis – year‑round allergies such as dust mites, pet dander, or moulds.

It is also appropriate for people who have not responded well to oral antihistamines or who prefer a topical treatment with minimal systemic side effects.

Who Should NOT Use Flixonase

Do not use Flixonase if:

  • You are allergic to fluticasone propionate or any of the other ingredients (listed in section 6 of the PIL), especially benzalkonium chloride or phenylethyl alcohol.
  • You have an untreated infection in your nose (e.g., cold sores, nasal herpes, or other viral, bacterial, or fungal infections) – treat the infection first.
  • You have recently had nasal surgery or an injury to your nose – wait until healing is complete.
  • You are under 4 years of age.

Consult your doctor before use if you have severe liver disease (as it may affect how your body processes the medicine) or if you are taking other steroid medicines (tablets, injections, or creams).

Taking Flixonase with Food and Without Food

Flixonase is a nasal spray that acts locally in the nose. It is not affected by food or drink. You can use it at any time of day, with or without meals. However, using it at the same time each day (e.g., after brushing your teeth in the morning) can help you remember.

There are no known interactions with food, alcohol, or beverages.

Special Conditions: Pregnancy, Breastfeeding & Other Considerations

Pregnancy: There is limited experience with fluticasone propionate in pregnant women. Studies in animals have shown some reproductive toxicity only at very high systemic doses, which are not reached with nasal use. Flixonase should only be used during pregnancy if clearly needed and after consulting your doctor. Uncontrolled allergic rhinitis itself can affect pregnancy (e.g., sneezing causing discomfort, sleep disturbance), so treatment may be beneficial.

Breastfeeding: It is not known whether fluticasone propionate passes into breast milk after nasal administration. Systemic absorption is minimal, so the amount ingested by a nursing infant is likely negligible. However, as a precaution, discuss with your doctor before using while breastfeeding.

Hepatic impairment: In people with severe liver disease, systemic exposure may increase. Your doctor may monitor you more closely, but no dose adjustment is usually needed.

Long‑term use in children: Regular use of nasal corticosteroids at recommended doses is safe, but height should be monitored periodically as a precaution.

Flixonase Usage FAQs

Simply skip the missed dose and take the next one at your regular time. Do not double the dose.

Yes, they can be used together. Flixonase targets the nasal inflammation, while antihistamines block systemic histamine. This combination is often prescribed.

Each bottle delivers 150 sprays. If you use the typical adult dose (2 sprays each nostril once daily = 4 sprays/day), it will last about 37 days.

Rinse your eyes immediately with plenty of cold water. If irritation persists, speak to your doctor or pharmacist.

Yes. Flixonase is a topical corticosteroid and does not affect blood pressure. It is safe for people with hypertension.

Need Flixonase Prescribed Online?

If you suffer from hayfever or perennial allergies, our UK‑registered doctors can assess your suitability and issue a prescription for Flixonase if appropriate.

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Nabeel M. - Medical Content Manager at Chemist Doctor
Authored byNabeel M.

Medical Content Manager

Nabeel is a co‑founder and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up‑to‑date.

Medical Doctor

Dr. Feroz is a GMC‑registered doctor and a medical reviewer at Chemist Doctor. He oversees acute condition and urgent care guidance.

Usman Mir - Superintendent Pharmacist
Approved byUsman Mir

Medical Director

Usman is a co‑founder and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.

Review Date: 13 March 2026

Next Review: 13 September 2026

Published on: 13 March 2026

Last Updated: 13 March 2026