Mometasone Furoate Nasal Spray

What is Mometasone Furoate?

Mometasone Furoate is a prescription nasal spray containing the active ingredient mometasone furoate monohydrate, a potent corticosteroid (often shortened to steroid) with strong anti-inflammatory properties. It's marketed under the brand name Beconase and is available as a 50 microgram per actuation nasal spray suspension.

Mechanism of Action

Mometasone Furoate works through a sophisticated anti-inflammatory mechanism:

• Inflammation reduction: Inhibits multiple inflammatory mediators including cytokines, chemokines, and adhesion molecules
• Mast cell stabilization: Reduces release of histamine and other allergy mediators
• Vasoconstriction: Decreases blood vessel permeability in nasal mucosa
• Immune modulation: Suppresses cellular immune responses in nasal tissues

Think of your nasal passages as a battlefield during allergy season - Mometasone Furoate acts like a peacekeeping force that calms the inflammatory response, reduces swelling, and prevents the "allergy cascade" from overwhelming your nasal defenses.

According to the British National Formulary, mometasone furoate has one of the lowest systemic bioavailability rates among nasal corticosteroids (<1%), making it particularly suitable for long-term use with minimal systemic effects.

What is Mometasone Furoate Used For?

Mometasone Furoate nasal spray is indicated for three main conditions as outlined in its UK marketing authorisation:

Approved Indications

Before Using Mometasone Furoate

Essential considerations before initiating treatment:

Medical History Assessment

• History of tuberculosis (active or latent)
• Current or recent nasal infections (bacterial, viral, fungal)
• Recent nasal surgery or trauma
• History of glaucoma or cataracts
• Immune system disorders or immunosuppressive therapy
• Cystic fibrosis (requires special monitoring)

Required Baseline Tests

1. Nasal examination for structural abnormalities
2. Assessment for active nasal infection
3. Review of current corticosteroid use (oral, inhaled, or other nasal)
4. Growth monitoring in children (height measurement)
5. Eye examination if history of glaucoma or cataracts

Mometasone Furoate Contraindications

Absolute contraindications where Mometasone Furoate must not be used:

Absolute Contraindications

• Hypersensitivity to mometasone furoate or any excipients
• Active untreated infection in the nose (bacterial, viral, fungal)
• Recent nasal surgery or nasal trauma (until fully healed)
• Active or latent tuberculosis (unless adequately treated)

Special Warnings

Special Population Considerations

Paediatric Patients (3-11 years)

• Lower dose required: 1 spray per nostril once daily
• Growth monitoring essential for long-term use
• Supervised administration recommended

Elderly Patients (≥65 years)

• No dose adjustment generally required
• Increased monitoring for nasal side effects
• Consider reduced manual dexterity affecting administration

Immunocompromised Patients

• Increased infection risk
• Avoid contact with chickenpox or measles
• Consider prophylactic measures if exposed

Mometasone Furoate and Other Medicines

Significant interactions requiring monitoring:

High-Risk Combinations

• Systemic corticosteroids: Increased risk of adrenal suppression
• Ritonavir/cobicistat (HIV medications): May increase mometasone levels
• Other nasal corticosteroids: Increased local side effects

Absorption Interactions

No specific timing requirements with other medications, but best used consistently at the same time each day for optimal symptom control.

Pregnancy & Breastfeeding

Pregnancy

• Limited human data available
• Use only if potential benefit justifies potential fetal risk
• Low systemic absorption (<1%) reduces theoretical risk
• Consult healthcare provider before use

Breastfeeding

• Unknown if mometasone is excreted in breast milk
• Low systemic absorption suggests minimal transfer
• Consider alternative non-medical measures first
• Consult healthcare provider for individual risk assessment

Driving & Machine Operation

• No direct impairment of driving ability
• Caution advised due to possible:
  • Dizziness (rare side effect)
  • Allergy symptoms themselves may impair concentration
• If you experience any unusual symptoms, avoid driving until assessed

Mometasone Furoate Ingredients

Active Substance

• Mometasone furoate monohydrate (50 micrograms per actuation)

Excipients

Important Allergen Information

• Benzalkonium chloride may cause nasal irritation
• Contains less than 1 mmol sodium (23 mg) per dose
• Essentially 'sodium-free'

How to Use Mometasone Furoate Nasal Spray

Preparation Steps

1. Wash hands thoroughly
2. Remove dust cap and shake bottle gently
3. Prime new bottle: Pump 10 times until fine mist appears
4. If unused for 14+ days: Re-prime with 2 pumps

Administration Technique

• Position: Hold bottle upright with thumb on base
• Angle: Insert nozzle into nostril, point away from septum
• Breathing: Breathe in slowly through nose during spray
• Rotation: Use both nostrils daily

Post-Administration Protocol

1. Breathe out through mouth after spraying
2. Wipe nozzle with clean tissue
3. Replace dust cap securely
4. Clean nozzle weekly to prevent blockage

Mometasone Furoate Dosage Guidelines

Standard Dosage Schedule

Nasal Polyps Dosage (Adults ≥18 only)

Administration Instructions

Step-by-step nasal spray guide:

Dose Preparation

1. Blow nose gently to clear passages
2. Shake bottle before each use
3. Remove dust cap
4. Hold bottle upright with thumb on base, fingers on collar

Spray Process

1. Close one nostril, insert nozzle into other nostril
2. Tilt head slightly forward
3. Breathe in slowly through nose
4. Press down firmly on collar to release spray
5. Breathe out through mouth
6. Repeat for second nostril if required

Post-Administration Care

• Do not sniff hard after administration
• Avoid tilting head back (increases throat drainage)
• Clean nozzle weekly with warm water
• Never use pins or sharp objects to unblock nozzle

Missed Dose Management

General Principles

• Do NOT double doses
• Take as soon as remembered if within 12 hours
• If >12 hours late, skip and resume next scheduled dose

Time-Based Guidance

Overdose Information

Symptoms

• Unlikely with nasal administration alone
• Increased nasal irritation
• Possible systemic effects with massive overdose

Management

1. Stop medication immediately
2. Rinse nasal passages with saline
3. Seek medical advice if concerned
4. Bring medication packaging to healthcare provider
5. No specific antidote - supportive care only

Possible Side Effects

Very Common (more than 1 in 10 people)

• Headache
• Sneezing (particularly after administration)
• Nosebleeds (epistaxis) - especially with nasal polyps treatment

Common (1 in 10 to 1 in 100 people)

• Sore nose or throat
• Nasal ulcers or irritation
• Upper respiratory tract infections
• Unpleasant taste or smell
• Cough

Serious Side Effects

How to Store Mometasone Furoate

Storage Conditions

• Store below 25°C
• Do not freeze
• Keep in original container
• Protect from direct sunlight

Stability Information

• Unopened: Until expiry date on packaging
• After first use: Use within 2 months
• Discard if solution discoloured or contains particles
• Never use after expiry date

Disposal

• Do not dispose in household waste or wastewater
• Return unused medication to pharmacy
• Follow local authority guidelines for medication disposal

Pack Information

Pack Sizes

• 1 x 140 spray bottle (approx. 2 months supply)
• 2 x 140 spray bottles (approx. 4 months supply)
• 3 x 140 spray bottles (approx. 6 months supply)

Components

• White opaque plastic vial with metered pump
• White nasal adaptor (nozzle)
• Translucent dust cap
• Patient information leaflet
• Outer carton with safety information

Appearance

• White suspension when shaken
• Delivers fine mist spray
• Each actuation delivers 50 micrograms
• Total content: Approximately 8.2g (140 sprays)

Where Can I Buy Mometasone Furoate Online in the UK