Nitrofurantoin Capsules
Nitrofurantoin is a prescription antibiotic for urinary tract infections in adults. Available in 50mg and 100mg capsules, it's effective against many UTI-causing bacteria. This medication is available through Chemist Doctor's regulated online service following a consultation with UK-licensed clinicians.
You must complete a short online consultation so that our prescriber can ensure that the treatment is suitable for you.
Assessment
Answer some questions about your health concerns & symptoms
Treatment
Connect with a clinician 100% online, no appointment needed
Delivery
Get your medication delivered directly, if prescribed
Table of Contents
- Nitrofurantoin 100mg for Urinary Tract Infections (UTIs)
- How Nitrofurantoin 100mg Works Against UTIs
- Nitrofurantoin Treatment for UTI: Duration and Effectiveness
- Nitrofurantoin 100mg Dosage Protocols
- How to Take Nitrofurantoin Correctly
- Nitrofurantoin Treatment for UTI: Safety Profile
- Where Can I Buy Nitrofurantoin Online in the UK
- Nitrofurantoin FAQs
Nitrofurantoin 100mg for Urinary Tract Infections (UTIs)
UTIs occur when bacteria like E. coli enter the urinary system. Women experience these infections more frequently due to anatomical differences:
- Shorter urethral length (3-4cm vs 20cm in males)
- Proximity between urethra and anus
Common triggers include sexual activity (NHS recommends post-coital urination), catheter use, and pregnancy-related bladder pressure. Chronic conditions like diabetes may increase susceptibility.
How Nitrofurantoin 100mg Works Against UTIs
This antibiotic concentrates in urine within 30 minutes of ingestion, achieving concentrations 200x higher than blood levels (eMC data). It disrupts bacterial enzymes and DNA synthesis through two mechanisms:
- Inhibits acetyl-CoA carboxylase, blocking fatty acid synthesis
- Generates reactive intermediates that damage bacterial DNA
This dual action makes nitrofurantoin particularly effective against common uropathogens while minimising systemic side effects.
Nitrofurantoin Treatment for UTI: Duration and Effectiveness
| Patient Group | Typical Course Length | Symptom Improvement |
|---|---|---|
| Women | 3 days | 48-72 hours |
| Men | 7 days | 5-7 days |
Complete the full prescribed course even if symptoms resolve earlier. Premature discontinuation risks antibiotic resistance and recurrent infections.
Nitrofurantoin 100mg Dosage Protocols
| Patient Group | Dose Frequency | Course Duration | Total Daily Dose |
|---|---|---|---|
| Women (uncomplicated) | 100mg twice daily | 3 days | 200mg |
| Men | 100mg twice daily | 7 days | 200mg |
| Prophylaxis | 50-100mg nightly | 6-12 months | 50-100mg |
Severe infections may require 100mg four times daily under medical supervision. Always complete your prescribed course to prevent antibiotic resistance.
How to Take Nitrofurantoin Correctly
Optimal Timing Strategies
- Twice-daily regimen: 12-hour intervals (e.g., 7am & 7pm)
- Four-times daily: Morning, midday, evening, bedtime
Administration Essentials
- Swallow capsules whole with 200ml water
- Take with food/milk to enhance absorption by 40% (eMC data)
- Avoid antacids within 2 hours of dose
Nitrofurantoin Treatment for UTI: Safety Profile
Common Side Effects (≥1% users)
- Gastrointestinal: Nausea (18%), vomiting (4%)
- Neurological: Headache (9%), dizziness (6%)
- Chromaturia: Harmless urine darkening (65%)
Serious Reactions Requiring Immediate Cessation
- Pulmonary toxicity (0.003% risk)
- Hepatitis (jaundice incidence: 0.4%)
- Peripheral neuropathy (0.07% cases)
Contraindications & Precautions
| Condition | Risk Level | Action Required |
|---|---|---|
| Renal impairment (eGFR <60) | High | Contraindicated |
| G6PD deficiency | Moderate | Monitor for hemolysis |
| Lactose intolerance | Low | Use lactose-free formulation |
Proper administration of nitrofurantoin 100mg is crucial for effective UTI treatment. This guide follows NICE clinical guidelines and MHRA safety recommendations.
Where Can I Buy Nitrofurantoin Online in the UK
Secure Nitrofurantoin Prescription & Next-Day Delivery Service
Order Nitrofurantoin with confidence through our UK-registered medical prescribers, who review all requests within 4 working hours. We guarantee same-day prescription approval for eligible patients and dispatch orders placed before 3pm for next-day tracked delivery.
Our Nitrofurantoin treatment service combines competitive pricing with strict adherence to MHRA safety standards, ensuring your medication is dispensed through GPhC-registered pharmacies. Every purchase includes discreet packaging and a GDPR-compliant consultation process.
Our Nitrofurantoin clinical team ensures:
- Full medical history review
- Drug interaction checks
- Ongoing safety monitoring
Always consult your GP for first-time symptoms or complex medical history.
Getting your medication is quick and easy with our simple 4-step process:
Start Consultation
Complete our brief health questionnaire about your medical history and current health.
Medical Review
UK-registered clinicians review your consultation for safe prescribing.
Pharmacy Processing
If approved, our partner pharmacy prepares your medication.
Fast Dispatch
Your order is dispatched via your chosen delivery method.
What does the online consultation involve?
You'll answer questions about your medical history and current health to ensure safe prescribing. Honest responses are vital for your safety.
How do I reorder medication?
Use the login details emailed after your first order to access your account and reorder.
How does the secure chat portal work?
Clinicians may contact you via your account's chat portal to discuss your treatment. Respond securely within your account.
At Chemist Doctor, we respect your privacy and ensure complete discretion at every step.
Discreet Packaging
All orders are shipped in discreet, tamper-evident packaging sealed inside anonymous mailing bags.
Secure Data
Your personal and medical information is kept strictly confidential with SSL encryption.
Private Consultations
All consultations are conducted privately by UK-registered clinicians.
Anonymous Billing
Credit card statements show a neutral descriptor with no reference to medications.
Will my GP be informed about my order?
Only with your consent. We recommend updating your GP directly for seamless care.
We offer two reliable delivery options to suit your needs:
| Service Type | Delivery Speed | Order Cut-off | Carrier |
|---|---|---|---|
| Standard Delivery | 2-3 business days | No cut-off | Royal Mail |
| Premium Next-Day Delivery | Next business day | 3 PM weekdays | Royal Mail 24 |
Next-day delivery guarantee applies to orders approved before 3 PM to these regions:
- England
- Scotland
- Wales
- Northern Ireland
Service Restrictions: We currently cannot deliver to: Republic of Ireland, Continental Europe, USA, or Canada
Is packaging discreet?
Yes. All orders are shipped in plain, unmarked packaging via tracked courier services.
Do I need to stay home for delivery?
No. You'll receive a tracking number to monitor your parcel's progress.
Do you deliver on weekends or bank holidays?
Deliveries occur Monday–Friday only. We do not ship on weekends or UK bank holidays.
What should I do if my order hasn't arrived?
Use your tracking number to locate the parcel or contact our support team for assistance.
Can I receive delivery updates via SMS?
Yes. Provide your mobile number at checkout for courier updates. We will not use it for marketing purposes.
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How long do refunds take to process?
Card payments: Refunds appear in 3–5 days.
Bank transfers: We'll contact you for account details to return funds.
Why was my order declined?
Declined orders are not charged. Card authorisations release funds within 3–5 days (contact your bank for details).
Can I return prescription medication?
No. UK law prohibits returns of dispensed prescription treatments for safety reasons.
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Nitrofurantoin FAQs
What is Nitrofurantoin 100mg used for?
Nitrofurantoin 100mg is an antibiotic used to treat bladder infections (cystitis) and urinary tract infections (UTIs). It may also be prescribed to prevent recurrent UTIs or before certain urinary tract procedures.
How long does Nitrofurantoin take to work?
Nitrofurantoin typically begins working within a few days, with most patients noticing symptom improvement after 2-3 days of treatment. Complete the full prescribed course even if symptoms improve earlier.
When should I take Nitrofurantoin?
Take Nitrofurantoin with food or milk, typically twice daily (every 12 hours). Common dosing times are with breakfast and dinner to help remember doses and minimise stomach upset.
Does Nitrofurantoin cause tiredness?
While fatigue isn't a direct side effect listed for Nitrofurantoin, the infection itself or other medication effects might cause tiredness. Consult your GP if persistent fatigue occurs during treatment.
Can I drink alcohol while taking Nitrofurantoin?
While no direct interaction exists, alcohol may worsen UTI symptoms and delay recovery. We recommend avoiding alcohol during treatment and for 48 hours after completing your course.
Can I take painkillers with Nitrofurantoin?
Common pain relievers like paracetamol or ibuprofen can generally be taken with Nitrofurantoin. For prescription pain medications or if unsure, consult your GP or pharmacist first.
Is Nitrofurantoin safe during pregnancy?
Nitrofurantoin may be used in early pregnancy but is generally avoided in the third trimester. Pregnant women with UTIs should consult their midwife or GP for appropriate treatment options.
Can Nitrofurantoin affect contraception?
Nitrofurantoin doesn't directly affect hormonal contraceptives. However, if you're sick (vomit) or have severe diarrhoea while taking it, your contraceptive may not work - use additional protection if this occurs.
Can Nitrofurantoin cause thrush?
Like many antibiotics, Nitrofurantoin may occasionally lead to thrush by disrupting natural bacterial balance. If thrush symptoms develop, consult your pharmacist or GP for treatment options.
Can I buy Nitrofurantoin over the counter?
No, Nitrofurantoin is a prescription-only medicine in the UK. You'll need to consult a GP or registered online doctor service to obtain it.
What if Nitrofurantoin doesn't work?
If symptoms persist after 3 days or worsen, consult your GP. Some UTIs may require alternative antibiotics if the bacteria are resistant to nitrofurantoin.
Can men take Nitrofurantoin for UTIs?
While primarily prescribed for women, men can be treated with Nitrofurantoin for UTIs under medical supervision. Male UTI symptoms should always be evaluated by a GP as they may indicate other conditions.
 | Authored by Nabeel M |
Medical Content Manager & Pharmacy Associate
Nabeel is a co-founder of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.
 | Reviewed by Usman M (2073618) |
Director & Superintendent Pharmacist
Usman is a co-founder, and superintendent pharmacist of Chemist Doctor. He leads the clinical team and online prescribing services, utilising his expertise.
Review Date: 08 May 2025
Next Review: 14 December 2025
Published on: 08 May 2025
Last Updated: 09 May 2025
Responsible Pharmacist
 | Usman Mir Superintendent GPhc: 2073618 |
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Chemist Doctor is an online pharmacy and online doctor service, owned and operated by Chem Doc Ltd (Company Reg. 16478812). Prescriptions are managed by our sister company, Inspire Pharmacy (GPhC No. 9011381), a registered pharmacy located at Unit 18, Croft Road Industrial Estate, Newcastle-under-Lyme, Staffordshire, ST5 0TW. The content on this website is for informational purposes only. It should support, not replace, advice from your healthcare provider. Always consult your doctor if you suspect a health issue or before beginning new medication. Ensure you read the leaflets provided with any medicines. For further details, visit our policies and terms & conditions at the bottom of each page.
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