How To Use Doxycycline Capsules
Follow these instructions carefully to ensure effective treatment and minimize side effects. Learn more about antibiotics.
Key Takeaways
- Swallow whole: Take with plenty of water while sitting/standing
- Timing: Avoid lying down for 30 minutes after dosing
- Food: Take with meals if treating acne or experiencing stomach upset
- Sun protection: High risk of sunburn - use SPF 30+
- Completion: Finish full course even if symptoms improve
Doxycycline is a broad-spectrum antibiotic used to treat various infections and prevent malaria. Proper administration is crucial for effectiveness and safety.
How to Take Doxycycline Capsules
- Swallow whole with a full glass of water (200mL). Do not chew, crush, or open the capsule.
- Stay upright for at least 30 minutes after taking to prevent throat irritation or ulcers.
- Timing:
- For infections: Take at the same time(s) daily, with or without food
- For acne: Always take with food or milk
- Avoid these within 2-3 hours of dosing:
- Antacids
- Iron/zinc supplements
- Dairy products (except small amounts with food)
Dosage Guidelines by Condition
| Condition | Initial Dose | Maintenance Dose | Duration |
|---|---|---|---|
| Chest/lung infections | 200mg | 100mg daily | 7-14 days |
| Acne | 50mg daily | 50mg daily | 6-12 weeks |
| Malaria prevention | 100mg daily (start 1-2 days before travel) | 100mg daily | Continue 4 weeks after return |
| Lyme disease | 200mg daily | 100mg twice daily | 10-21 days |
| Children (8-12 years)* | 4.4mg/kg | 2.2mg/kg daily | Varies by infection |
*Only used when alternatives unavailable. Children ≥45kg use adult dosing.
Missed Dose
Take as soon as remembered unless close to next dose. Never double dose.
Treatment Timeline
- Day 1-2: Symptoms may begin improving (except acne)
- Day 3-7: Complete full course even if feeling better
- Week 2-12 (acne): Gradual improvement; may worsen initially
- After treatment:
- Sun sensitivity may persist 1-2 weeks
- Report any delayed diarrhea (can occur 2 months post-treatment)
Important Precautions
- Severe headache/vision changes (intracranial hypertension)
- Difficulty swallowing or chest pain
- Skin blistering or severe sunburn
Essential Tips
- Sun protection: Wear SPF 30+, cover skin, avoid sunbeds
- Drug interactions: Avoid antacids, iron, zinc, or bismuth subsalicylate (Pepto-Bismol®)
- Pregnancy test: Required for women of childbearing age before starting
- Storage: Keep below 25°C in original packaging
Frequently Asked Questions
Can I take Doxycycline on an empty stomach?
For most infections, yes. For acne or if stomach upset occurs, take with food. Avoid dairy within 2 hours.
Why can't I lie down after taking it?
To prevent the capsule from sticking to your esophagus, which can cause painful inflammation or ulcers.
What if I vomit after taking a dose?
If vomiting occurs within 30 minutes, take another dose. After 30 minutes, wait until next scheduled dose.
Can I drink alcohol with Doxycycline?
Avoid alcohol—it may increase side effects like nausea and reduce effectiveness.
How should I store Doxycycline capsules?
Store below 25°C in the original package. Keep dry and away from sunlight.
Need Treatment for malaria
If you're experiencing symptoms of a bacterial infection, our UK-registered doctors can help determine if Doxycycline Capsules is appropriate for your condition through a confidential online consultation.
Secure Prescription & Next-Day Delivery
MHRA-compliant | GPhC-registered pharmacy | Discreet packaging
Start UTI ConsultationRelated Guides
Medical Content Manager
Nabeel is a co-founder and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.
Medical Doctor
Dr. Feroz is a GMC-registered doctor and a medical reviewer at Chemist Doctor. He oversees acute condition and urgent care guidance.
Medical Director
Usman is a co-founder and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.
Review Date: 03 November 2025
Next Review: 05 May 2026
Published on: 03 November 2025
Last Updated: 04 November 2025
