How To Use Veoza

How to Take Veoza: Step‑by‑Step Usage Guide

1. Check suitability: Before starting, confirm with your doctor that you are not taking any medicines that interact with Veoza (see section “Who Should Not Use Veoza”).
2. Choose a consistent time: Pick a time of day that is easy to remember – for example, after breakfast or before bed. Taking it at the same time each day helps maintain stable levels in your body.
3. Prepare the tablet: Remove one tablet from the blister pack. Inspect it to ensure it is intact (round, light red, debossed with company logo and “645”).
4. Swallow whole: Place the tablet in your mouth and swallow it with a glass of water. Do not break, crush, or chew the tablet – this can affect how the medicine is absorbed.
5. With or without food: Veoza can be taken either with or without food. Choose whichever suits your routine.
6. If you forget a dose: If you remember on the same day and there are at least 12 hours until your next scheduled dose, take the missed tablet as soon as possible. If less than 12 hours remain, skip the missed dose and resume your regular schedule the next day. Never take a double dose to make up for a forgotten one.
7. Do not stop early: Continue taking Veoza for as long as your doctor prescribes. Stopping prematurely may cause your symptoms to return. Always consult your doctor before discontinuing treatment.

Dosage Guide: Recommended Dose and Schedule

The recommended dose of Veoza is one 45 mg tablet taken once daily. This dose has been shown in clinical trials to effectively reduce the frequency and severity of menopausal hot flashes and night sweats.

• Standard dose: 45 mg once daily – no dose adjustment is needed for age, weight, or mild‑to‑moderate renal impairment.
• Duration: Treatment is usually continued as long as symptoms are bothersome and the medicine remains effective. Your doctor will review your treatment periodically.
• Missed dose instructions: As above, take within same day if ≥12 hours until next dose, otherwise skip. Do not double dose.
• Overdose: If you accidentally take more than one tablet, contact your doctor or pharmacist immediately. Symptoms of overdose may include headache, nausea, or tingling sensations.

Who Should Use Veoza

Veoza is indicated for menopausal women who experience moderate‑to‑severe vasomotor symptoms (hot flashes and night sweats). It is a non‑hormonal option, making it suitable for:

• Women who cannot or prefer not to use hormone replacement therapy (HRT).
• Women with a history of hormone‑sensitive conditions where oestrogen is contraindicated.
• Women seeking a non‑hormonal alternative with a central mechanism of action.

Veoza is intended for women aged 18 years and older who have reached natural or surgical menopause. Your doctor will assess your medical history to confirm that Veoza is appropriate for you.

Who Should Not Use Veoza

Do not take Veoza if any of the following apply to you:

• Allergy: You are allergic to fezolinetant or any of the other ingredients (see section 6 of the PIL).
• Concomitant CYP1A2 inhibitors: You are taking strong or moderate CYP1A2 inhibitors, such as:
  • Fluvoxamine (for depression/anxiety)
  • Enoxacin (an antibiotic)
  • Mexiletine (for muscle stiffness)
  • Ethinyl oestradiol‑containing contraceptives (birth control pills)
  These medicines can significantly increase Veoza levels in your blood, raising the risk of side effects.
• Pregnancy or breastfeeding: Veoza is not for use during pregnancy or while breastfeeding. If you become pregnant while taking it, stop immediately and inform your doctor.
• Liver disease: If you have active liver disease or significant liver impairment, Veoza is not recommended. Your doctor may monitor liver enzymes periodically if you have pre‑existing liver issues.
• Kidney problems: Severe renal impairment has not been studied; your doctor may avoid prescribing Veoza if you have severe kidney disease.
• History of breast cancer or other oestrogen‑related cancer: Safety in these populations has not been established; therefore, Veoza should not be used.
• Seizure history: Veoza has not been studied in women with a history of seizures and is generally not recommended.
• Concomitant hormone replacement therapy (HRT): The combination has not been studied; your doctor will likely advise against using both together.

Children and adolescents under 18 years of age should not take Veoza, as it is specifically for menopausal women.

Taking Veoza With Food and Without Food

Veoza can be taken either with or without food. Clinical studies have shown that food does not significantly affect the absorption of fezolinetant, so you can choose the option that best fits your daily routine.

• With food: Taking Veoza after a meal may help some people remember to take it consistently. There is no requirement to take it with a high‑fat or specific type of meal.
• Without food: If you prefer to take it on an empty stomach, that is equally acceptable.

The key is to take it at the same time each day, regardless of meals, to maintain steady levels in your body.

Special Conditions: Pregnancy, Breastfeeding, and Other Considerations

Pregnancy: Veoza is strictly contraindicated during pregnancy. If you are a woman of childbearing potential, you must use effective non‑hormonal contraception while taking Veoza. If you become pregnant, stop the medicine immediately and consult your doctor.

Breastfeeding: It is not known whether fezolinetant passes into human breast milk. Due to the potential risk to the infant, breastfeeding is not recommended during treatment with Veoza.

Liver disease: If you have ongoing liver problems, your doctor may perform blood tests to check your liver enzymes before and during treatment. If levels become significantly elevated, treatment may be stopped.

Kidney impairment: Mild‑to‑moderate renal impairment does not require dose adjustment. Severe renal impairment has not been studied, so Veoza should be avoided in this group.

Driving and using machines: Veoza has no known effect on the ability to drive or operate machinery.

Veoza FAQs

Need Veoza with Personalised Advice?

If you are experiencing moderate‑to‑severe hot flashes and night sweats, a UK‑registered doctor can assess whether Veoza is right for you. Our online service provides convenient access to prescription and next‑day delivery.

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