Priligy Tablets

What is Priligy?

Priligy is a prescription medication specifically developed to treat premature ejaculation (PE). Its active ingredient is Dapoxetine, which belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). While other SSRIs are used daily for depression and anxiety, Dapoxetine is unique due to its rapid absorption and short duration of action, making it suitable for on-demand use for PE.

How Does Priligy Work?

Priligy works by increasing the activity of serotonin, a key chemical messenger (neurotransmitter) in the brain involved in mood, appetite, and sexual function. Think of serotonin like a "control signal" for ejaculation. Priligy enhances this signal by slowing its reabsorption in the brain, effectively giving the body more time to control the ejaculation reflex. This biological pathway helps to delay ejaculation and improve control for men suffering from premature ejaculation.

What is Priligy Used For?

Priligy is indicated for the treatment of premature ejaculation (PE) in adult men aged 18 to 64 years. Premature ejaculation is defined as a persistent or recurrent pattern of ejaculation occurring during partnered sexual activity within approximately one minute of vaginal penetration and before the person wishes it, causing distress and frustration.

Before Using Priligy

Before starting treatment with Priligy, your clinician will assess your medical history to ensure it is safe for you. Be prepared to discuss the following:

Medical History Assessment

• History of fainting or dizziness
• Heart problems (e.g., heart failure, irregular heartbeat)
• Liver or kidney disease
• Bleeding or blood clotting disorders
• Epilepsy or seizures
• Mental health conditions (e.g., depression, bipolar disorder, mania, schizophrenia)
• Glaucoma (high pressure in the eye)

Lifestyle Factors

Your use of recreational drugs or alcohol.

Your doctor may perform a test to check if your blood pressure drops significantly when you stand up, as Priligy can cause orthostatic hypotension (a form of low blood pressure).

Priligy Contraindications

Do NOT take Priligy if you have any of the following:

Absolute Contraindications

• Allergy to Dapoxetine or any other ingredient in Priligy
• Significant heart problems (heart failure, rhythm problems)
• History of fainting
• History of mania or severe depression
• Moderate or severe liver problems
• You are taking certain interacting medicines

High-Risk Medication Combinations

Special Population Considerations

Elderly Patients (Over 65)

• Priligy is not recommended for men over 65 due to a lack of safety and efficacy data in this age group

Adolescents (Under 18)

• Priligy must not be used by individuals under 18 years of age

Renal Impairment

• Use with caution in men with mild to moderate kidney problems
• Not recommended for those with severe kidney impairment

Hepatic Impairment

• Priligy is contraindicated in moderate or severe liver impairment
• It can be used with caution in mild liver impairment

Priligy and Other Medicines

Priligy can interact with many other medicines. It is crucial to tell your doctor about all the medicines you are taking, including prescription, over-the-counter, and herbal remedies.

Do not take Priligy with the following:

(wait 14 days after stopping these before starting Priligy, and 7 days after stopping Priligy before starting these):

• Monoamine oxidase inhibitors (MAOIs) for depression
• Other medicines for depression (e.g., SSRIs, SNRIs, tricyclics)
• Lithium (for bipolar disorder)
• Linezolid (an antibiotic)
• Tryptophan (a sleep aid)
• St. John's Wort (a herbal remedy)
• Tramadol (a strong painkiller)
• Medicines for migraines (e.g., triptans)
• Strong CYP3A4 inhibitors: Certain antifungals (ketoconazole, itraconazole), HIV medicines (ritonavir, saquinavir), and antibiotics (telithromycin)

Use with caution and inform your doctor if you are taking:

• Medicines for erectile dysfunction (e.g., Sildenafil, Tadalafil) as they may also lower blood pressure
• Medicines for high blood pressure or an enlarged prostate that can lower blood pressure
• Blood thinners (e.g., Warfarin)
• Non-steroidal anti-inflammatory drugs (NSAIDs) like Ibuprofen

Pregnancy & Breastfeeding

Priligy is strictly for use by adult men and should not be taken by women. It is not indicated for use during pregnancy or breastfeeding. If a female partner is pregnant or could become pregnant, it is important to discuss this with your doctor, though the risk from a single dose via semen is considered very low.

Driving & Machine Operation

Priligy may cause dizziness, sleepiness, blurred vision, or fainting. Do not drive, cycle, or operate machinery if you experience any of these effects. The risk is increased if Priligy is taken with alcohol. You must understand how you react to Priligy before engaging in any potentially hazardous activities.

Priligy Ingredients

Active Substance

• Dapoxetine (as hydrochloride)

Other Ingredients (Excipients)

Allergen Warning

• This medicine contains lactose (a milk sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

How to Use Priligy

Priligy is taken orally as needed, not on a daily basis.

Priligy Dosage Guidelines

Standard Dosage Schedule

Your doctor will usually recommend starting with the 30 mg dose. Do not take more than one tablet per day. Discuss your treatment with your doctor after 4 weeks or 6 doses to assess its continued use.

Administration Instructions

Step-by-step administration guide:

Dosage Timing

1. Take one tablet 1 to 3 hours before you anticipate sexual activity
2. Do not take more than one dose in 24 hours

Administration Process

1. Swallow the tablet whole with a full glass of water to avoid a bitter taste and help reduce the risk of fainting
2. Priligy can be taken with or without food

Missed Dose Management

As Priligy is taken on an "as-needed" basis, the concept of a "missed dose" does not apply. Simply take one tablet 1-3 hours before your next anticipated sexual activity, ensuring at least 24 hours have passed since your last dose.

Overdose Information

Symptoms

• Severe dizziness
• Lightheadedness
• Fainting
• Nausea and vomiting

Management

1. Seek immediate medical attention
2. Bring medication packaging
3. Symptomatic treatment as required

Possible Side Effects

Like all medicines, Priligy can cause side effects, although not everybody gets them.

Stop taking Priligy and see a doctor straight away if you experience:

• Fits (seizures)
• Fainting or feeling lightheaded when you stand up
• Noticeable changes in your mood
• Any thoughts of suicide or harming yourself

Side Effects by Frequency

Very Common (affects more than 1 in 10 men)

• Dizziness
• Headache
• Nausea

Common (affects up to 1 in 10 men)

• Irritability, anxiety, restlessness
• Numbness or 'pins and needles'
• Erectile dysfunction, decreased libido
• Sweating, flushing
• Diarrhoea, constipation, stomach pain, bloating, vomiting
• Insomnia, strange dreams
• Tiredness, sleepiness, yawning
• Nasal congestion, blurred vision, dry mouth, indigestion

Uncommon (affects up to 1 in 100 men)

• Fainting upon standing
• Mood swings, confusion
• Slow/irregular heartbeat
• Vision problems
• Low/high blood pressure

Rare (affects up to 1 in 1,000 men)

• Dizziness after exertion
• Sudden onset of sleep
• Urgency to have a bowel movement

You can report suspected side effects via the Yellow Card Scheme.

How to Store Priligy

Storage Conditions

• Store in the original package to protect from moisture
• Keep out of the sight and reach of children
• Do not use after the expiry date printed on the carton

Disposal

• Do not dispose of medicines via wastewater or household waste
• Ask your pharmacist how to dispose of medicines you no longer use

Pack Information

Pack Sizes

• Priligy is supplied in blister packs containing 1, 2, 3, or 6 film-coated tablets
• Not all pack sizes may be available

Appearance

• Priligy 30 mg: Light grey, round, convex tablet, marked "30" inside a triangle
• Priligy 60 mg: Grey, round, convex tablet, marked "60" inside a triangle

Where Can I Buy Priligy Online in the UK