How To Use Saxenda Injection Complete Guide
Proper administration of your Saxenda pen ensures optimal results. Follow this NHS-approved technique for safe subcutaneous injections.
Key Takeaways
- Dose Escalation: Start at 0.6mg/day, increase weekly to 3.0mg over 5 weeks
- Injection Sites: Rotate between abdomen, thighs and upper arms
- Timing: Inject at any time of day (consistent timing recommended)
- Needle Safety: Always use new NovoFine/NovoTwist needles (not included)
- Storage: Refrigerate unused pens; in-use pens stable at ≤30°C for 1 month
This guide provides comprehensive instructions for safely and effectively using your Saxenda pen for weight loss treatment.
Preparing Your Saxenda Pen
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Check the Pen
Verify the label shows "Saxenda 6 mg/ml". Inspect the solution through the window - it should be clear and colourless. Do not use if cloudy.
-
Attach a New Needle
Use only NovoFine (30G-32G) or NovoTwist needles (sold separately). Remove the pen cap, peel the needle tab, and screw the needle on tightly.
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Remove Needle Caps
Pull off both the outer and inner needle caps. Save the outer cap for later disposal. A small drop may appear at the needle tip - this is normal.
-
Perform Flow Check (New Pens Only)
Turn the dose selector to the flow check symbol (⚡). Hold pen upright and press the dose button until 0 aligns with the pointer. A drop should appear at the needle tip.
Step-by-Step Injection Technique
Abdomen
At least 5cm from navel
Thigh
Upper outer area
Upper Arm
Back of upper arm
-
Select Your Dose
Turn the dose selector until the counter shows your prescribed dose (0.6mg, 1.2mg, 1.8mg, 2.4mg or 3.0mg). The pointer must align exactly with your dose.
-
Clean Injection Site
Wash hands, then clean the skin with an alcohol swab. Let it dry completely before injecting.
-
Insert the Needle
Pinch a fold of skin and insert the needle at 90° (or 45° if very lean). Keep fingers clear of the dose counter.
-
Deliver the Dose
Press and hold the dose button until the counter returns to 0. Listen for the click. Keep holding for 6 seconds to ensure full dose delivery.
-
Remove and Dispose
Withdraw the needle, then safely recap using the outer needle cap. Unscrew and dispose in a sharps bin. Never reuse needles.
Pro Tip: Rotate injection sites daily to prevent lipohypertrophy (lumpy skin). Track locations using a body map diary.
Saxenda Dose Escalation Schedule
| Week | Daily Dose | Pen Clicks* | Key Points |
|---|---|---|---|
| Week 1 | 0.6 mg | 10 clicks | Helps body adjust; mild nausea common |
| Week 2 | 1.2 mg | 20 clicks | Appetite suppression begins |
| Week 3 | 1.8 mg | 30 clicks | Maximum dose for some patients |
| Week 4 | 2.4 mg | 40 clicks | Continue if tolerating well |
| Week 5+ | 3.0 mg | 50 clicks | Maintenance dose; assess response at 12 weeks |
*Based on NovoFine 32G 4mm needles - actual clicks may vary by needle type
Storage & Handling
- Unopened pens: Refrigerate at 2-8°C (do not freeze). Keep in original box.
- In-use pens: May be stored at ≤30°C for up to 1 month. Keep pen cap on when not in use.
- Travelling: Use a cool bag if temperatures exceed 30°C. Never leave in a hot car.
- Disposal: Place used needles in a sharps bin. Empty pens can go in household waste (without needle attached).
Expiry Alert: The pen expiry date changes once in use. Write the 1-month use-by date on the label after first use.
Frequently Asked Questions
What should I do if I see blood after injecting?
Apply light pressure with gauze for 30 seconds. Small bleeds are normal. Only worry if bleeding persists >5 minutes or you notice significant bruising.
Can I reuse the same needle to save money?
No. Reusing needles causes: (1) Blocked injections (2) Increased pain (3) Infection risk. Always use a new sterile needle for each injection.
Why does my pen sometimes leak after injection?
This happens if you remove the needle too quickly. Always count to 6 while holding the dose button down, then wait 2 more seconds before withdrawing.
How do I know if my Saxenda pen is empty?
The dose counter won't turn to your full dose (e.g., stops at 2.7mg when trying to select 3.0mg). You may also see <0.3ml solution in the window.
Is it normal to feel stinging during injection?
Mild stinging for 10-15 seconds is common, especially with higher doses. If pain persists, try: (1) Room-temperature pens (2) Different injection sites (3) Numbing the area with ice first.
Ready to Start Your Weight Loss Journey?
If you're struggling to lose weight through diet and exercise alone, our UK-registered doctors can help determine if Saxenda Injection is appropriate for your condition through a confidential online consultation.
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Medical Content Manager
Nabeel is a co-founder and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.
Medical Doctor
Dr. Talal is a GMC registered doctor and medical reviewer at Chemist Doctor. He ensures clinical accuracy and reliability across health content.
Medical Director
Usman is a co-founder and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.
Review Date: 18 November 2025
Next Review: 20 May 2026
Published on: 18 November 2025
Last Updated: 19 November 2025
