Proctosedyl Side Effects Guide
Key Takeaways
- Common side effects: Mild burning/itching (10-20% of users)
- Onset: Usually within first 3 days of use
- Duration: Typically resolve within 48 hours of stopping
- Serious reactions: Skin thinning with prolonged use (>7 days)
- Contraindications: Avoid with tuberculosis or viral infections in treatment area
While Proctosedyl ointment is generally well-tolerated when used as directed, understanding potential side effects helps patients use this medication safely. This evidence-based guide details the frequency and duration of possible reactions (from common temporary burning or itching to rare but important systemic effects from prolonged steroid use), compares Proctosedyl's safety profile to other haemorrhoid treatments, and provides clinically-validated strategies for minimizing discomfort while maximizing therapeutic benefits.
Common Side Effects of Proctosedyl Ointment
Proctosedyl contains two active ingredients that may cause different reactions:
| Ingredient | Common Reactions | Frequency |
|---|---|---|
| Hydrocortisone (5mg/g) | Mild burning, itching, skin dryness | 1 in 10 users |
| Cinchocaine (5mg/g) | Temporary numbness, local irritation | 1 in 20 users |
| Combined effect | Redness, swelling at application site | 1 in 50 users |
These reactions are usually mild and don't require discontinuation unless persistent or severe.
When Do Proctosedyl Side Effects Start?
Side effect onset follows distinct patterns:
Immediate Reactions (Within 1 Hour)
- Temporary numbness (cinchocaine effect)
- Cooling sensation from base ingredients
Early Reactions (24-72 Hours)
- Burning/itching sensation
- Mild redness around application site
Delayed Reactions (After 5+ Days)
- Skin thinning (with prolonged steroid use)
- Increased skin sensitivity
How Long Do Proctosedyl Side Effects Last?
| Side Effect | Typical Duration | Management |
|---|---|---|
| Burning/itching | 24-48 hours after last use | Apply cold compress |
| Numbness | 1-2 hours post-application | Normal effect of local anaesthetic |
| Skin redness | 3-5 days | Discontinue if persistent |
| Skin thinning | Weeks-months (if used >7 days) | Requires medical assessment |
Most users report complete resolution of side effects within:
- Mild reactions: 1-2 days after stopping
- Moderate reactions: 3-5 days with proper care
Serious Side Effects Requiring Medical Attention
Stop use immediately and contact your doctor if you experience:
- Severe skin reactions (peeling, blistering)
- Worsening pain/swelling
- Signs of systemic absorption (weight gain, moon face)
- Rectal bleeding that soaks through clothing
Risk Factors for Severe Reactions
- Use beyond recommended 7-day limit
- Application to broken skin
- Concurrent use with other steroid products
- Children under 12 years
FAQs
Can Proctosedyl make haemorrhoids worse?
In rare cases (∼1%), prolonged use may cause skin thinning that exacerbates symptoms. Discontinue if symptoms worsen after 3 days.
Why does Proctosedyl burn when first applied?
The cinchocaine component may cause temporary stinging (15-30 seconds) as it numbs nerve endings. This typically resolves with continued use.
Can I use Proctosedyl long-term?
No. Maximum use is 7 consecutive days due to steroid-related risks like skin atrophy and systemic absorption.
Does Proctosedyl affect bowel movements?
Not directly, but 2% of users report temporary constipation from reduced anal sensitivity due to the local anaesthetic effect.
 | Authored by Nabeel |
Medical Content Manager
Nabeel is a co-founder, and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.
 | Reviewed by Dr. Waqas (GMC:7928708) |
Medical Doctor
Dr. Waqas is a GMC-registered doctor at Chemist Doctor, specialising in general health. He balances clinical precision with cultural sensitivity.
 | Approved by Usman |
Medical Director
Usman is a co-founder, and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.
Review Date: 12 August 2025
Next Review: 14 February 2026
Published on: 11 August 2025
Last Updated: 12 August 2025
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