How Long Does Proctosedyl Take To Work: Efficacy Timeline
Key Takeaways
- Initial relief: 15-30 minutes (numbing effect from cinchocaine)
- Peak anti-inflammatory effect: 24-48 hours (hydrocortisone action)
- Duration: Apply 2-3 times daily for ≤7 days
- Avoid if: Tuberculosis/viral/fungal infections in the area
- Warning: Prolonged steroid use may thin anal skin
Understanding Proctosedyl ointment's efficacy timeline helps set realistic expectations for haemorrhoid relief. This guide explains when you can expect pain relief (often within 15-30 minutes from the local anaesthetic) and reduced inflammation (typically within 24-48 hours) based on clinical studies and real-world experience with internal and external piles.
Proctosedyl Efficacy Timeline
| Time After Application | Biological Effect | Symptom Relief |
|---|---|---|
| 5-15 minutes | Cinchocaine blocks nerve signals | Numbing sensation begins |
| 30 minutes | Local anaesthetic peaks | Significant pain reduction |
| 4-6 hours | Hydrocortisone reduces inflammation | Swelling starts to decrease |
| 24-48 hours | Maximum anti-inflammatory effect | Improved bowel movement comfort |
| 3-7 days | Sustained treatment | Haemorrhoid symptoms resolve (mild cases) |
Clinical Note: For severe haemorrhoids, relief may take longer. Consult a doctor if no improvement after 7 days.
How to Apply Proctosedyl Correctly
- Wash hands before and after application
- Clean the anal area gently with mild soap
- Attach applicator nozzle to the tube
- Insert 1-2cm into rectum and squeeze a pea-sized amount
- Apply externally if external piles are present
- Use 2-3 times daily (morning, evening, and after bowel movements)
- Bleeding worsens or persists beyond 3 days
- Signs of infection appear (pus, fever)
- Severe skin irritation develops
Active Ingredients & How They Work
| Ingredient | Concentration | Mechanism |
|---|---|---|
| Cinchocaine HCl | 0.5% | Blocks sodium channels to numb pain signals |
| Hydrocortisone | 0.5% | Inhibits inflammatory cytokines (IL-1, TNF-α) |
Synergistic Effects
- Fast-acting: Cinchocaine provides immediate pain relief
- Long-term healing: Hydrocortisone reduces swelling over days
- Dual-action: Targets both symptoms and causes of discomfort
FAQs
How quickly does Proctosedyl work?
Cinchocaine numbs pain within minutes; hydrocortisone reduces swelling over 24-48 hours.
How long until I see full effect from Proctosedyl?
Pain relief begins within 30-60 minutes. Swelling typically reduces within 24-48 hours. Full effect for itching may take 3-5 days.
What if Proctosedyl doesn't work after 7 days?
Consult your GP. Persistent symptoms may indicate infection or need for procedural treatment (e.g., banding).
 | Authored by Nabeel |
Medical Content Manager
Nabeel is a co-founder, and medical content manager of Chemist Doctor. He works closely with our medical team to ensure the information is accurate and up-to-date.
 | Reviewed by Dr. Waqas (GMC:7928708) |
Medical Doctor
Dr. Waqas is a GMC-registered doctor at Chemist Doctor, specialising in general health. He balances clinical precision with cultural sensitivity.
 | Approved by Usman |
Medical Director
Usman is a co-founder, and medical director of Chemist Doctor. He leads the organisation's strategic vision, bridging clinical and operational priorities.
Review Date: 12 August 2025
Next Review: 14 February 2026
Published on: 11 August 2025
Last Updated: 12 August 2025
